Thyroid gland metastasis from breast cancer: a case report
Primary cancer metastasis to thyroid gland is rare. The most common metastatic tumors of the thyroid gland are from lung, breast and renal cell carcinoma. In this case report, a patient with breast cancer metastasized to the thyroid gland is presented. A 38-year-old female patient was diagnosed with...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences Press
2020-02-01
|
| Series: | Journal of Research in Clinical Medicine |
| Subjects: | |
| Online Access: | https://jrcm.tbzmed.ac.ir/PDF/jrcm-8-15.pdf |
| _version_ | 1818863208582086656 |
|---|---|
| author | Mehmet Sözen Zeynep Cantürk Berrin Çetinarslan Alev Selek Emre Gezer Çiğdem Vural Umay Kiraz |
| author_facet | Mehmet Sözen Zeynep Cantürk Berrin Çetinarslan Alev Selek Emre Gezer Çiğdem Vural Umay Kiraz |
| author_sort | Mehmet Sözen |
| collection | DOAJ |
| description | Primary cancer metastasis to thyroid gland is rare. The most common metastatic tumors of the thyroid gland are from lung, breast and renal cell carcinoma. In this case report, a patient with breast cancer metastasized to the thyroid gland is presented. A 38-year-old female patient was diagnosed with breast cancer, and positron emission tomography-computed tomography (PET-CT) imaging for breast cancer staging revealed fluoro-2deoxy-D-glucose (FDG) uptake in the thyroid nodule. Fine needle aspiration biopsy (FNAB) of the nodule revealed atypia of undetermined significance (Bethesda III). After neoadjuvant chemotherapy, simultaneous breast conserving surgery and total thyroidectomy were performed. Immunohistochemical staining of the pathological specimens revealed breast cancer that had metastasized to the thyroid gland. Immunohistochemical methods helped distinguishing primary thyroid cancer from metastasis. Also, nodules that showed activity involvement were detected randomly in PET-CT, and had to be evaluated in terms of malignancy. |
| first_indexed | 2024-12-19T10:12:07Z |
| format | Article |
| id | doaj.art-55eefe794b824fb2bf67855db1922539 |
| institution | Directory Open Access Journal |
| issn | 2717-0616 |
| language | English |
| last_indexed | 2024-12-19T10:12:07Z |
| publishDate | 2020-02-01 |
| publisher | Tabriz University of Medical Sciences Press |
| record_format | Article |
| series | Journal of Research in Clinical Medicine |
| spelling | doaj.art-55eefe794b824fb2bf67855db19225392022-12-21T20:26:20ZengTabriz University of Medical Sciences PressJournal of Research in Clinical Medicine2717-06162020-02-0181151510.34172/jrcm.2020.015jrcm-31787Thyroid gland metastasis from breast cancer: a case reportMehmet Sözen0Zeynep Cantürk1Berrin Çetinarslan2Alev Selek3Emre Gezer4Çiğdem Vural5Umay Kiraz6Division of Endocrinology and Metabolism, Department of Internal Medicine, Kocaeli University College of Medicine, Kocaeli, TurkeyDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kocaeli University College of Medicine, Kocaeli, TurkeyDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kocaeli University College of Medicine, Kocaeli, TurkeyDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kocaeli University College of Medicine, Kocaeli, TurkeyDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kocaeli University College of Medicine, Kocaeli, TurkeyDepartment of Pathology, Kocaeli University College of Medicine, Kocaeli, TurkeyDepartment of Pathology, Kocaeli University College of Medicine, Kocaeli, TurkeyPrimary cancer metastasis to thyroid gland is rare. The most common metastatic tumors of the thyroid gland are from lung, breast and renal cell carcinoma. In this case report, a patient with breast cancer metastasized to the thyroid gland is presented. A 38-year-old female patient was diagnosed with breast cancer, and positron emission tomography-computed tomography (PET-CT) imaging for breast cancer staging revealed fluoro-2deoxy-D-glucose (FDG) uptake in the thyroid nodule. Fine needle aspiration biopsy (FNAB) of the nodule revealed atypia of undetermined significance (Bethesda III). After neoadjuvant chemotherapy, simultaneous breast conserving surgery and total thyroidectomy were performed. Immunohistochemical staining of the pathological specimens revealed breast cancer that had metastasized to the thyroid gland. Immunohistochemical methods helped distinguishing primary thyroid cancer from metastasis. Also, nodules that showed activity involvement were detected randomly in PET-CT, and had to be evaluated in terms of malignancy.https://jrcm.tbzmed.ac.ir/PDF/jrcm-8-15.pdfbreast cancerthyroid glandmetastasis |
| spellingShingle | Mehmet Sözen Zeynep Cantürk Berrin Çetinarslan Alev Selek Emre Gezer Çiğdem Vural Umay Kiraz Thyroid gland metastasis from breast cancer: a case report Journal of Research in Clinical Medicine breast cancer thyroid gland metastasis |
| title | Thyroid gland metastasis from breast cancer: a case report |
| title_full | Thyroid gland metastasis from breast cancer: a case report |
| title_fullStr | Thyroid gland metastasis from breast cancer: a case report |
| title_full_unstemmed | Thyroid gland metastasis from breast cancer: a case report |
| title_short | Thyroid gland metastasis from breast cancer: a case report |
| title_sort | thyroid gland metastasis from breast cancer a case report |
| topic | breast cancer thyroid gland metastasis |
| url | https://jrcm.tbzmed.ac.ir/PDF/jrcm-8-15.pdf |
| work_keys_str_mv | AT mehmetsozen thyroidglandmetastasisfrombreastcanceracasereport AT zeynepcanturk thyroidglandmetastasisfrombreastcanceracasereport AT berrincetinarslan thyroidglandmetastasisfrombreastcanceracasereport AT alevselek thyroidglandmetastasisfrombreastcanceracasereport AT emregezer thyroidglandmetastasisfrombreastcanceracasereport AT cigdemvural thyroidglandmetastasisfrombreastcanceracasereport AT umaykiraz thyroidglandmetastasisfrombreastcanceracasereport |