TRPA1 Polymorphisms Modify the Hypotensive Responses to Propofol with No Change in Nitrite or Nitrate Levels

TRPA1 Polymorphisms Modify the Hypotensive Responses to Propofol with No Change in Nitrite or Nitrate Levels

Anesthesia with propofol is frequently associated with hypotension. The <i>TRPA1</i> gene contributes to the vasodilator effect of propofol. Hypotension is crucial for anesthesiologists because it is deleterious in the perioperative period. We tested whether the <i>TRPA1</i>...

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Bibliographic Details
Main Authors: Isabela Borges de Melo, Gustavo H. Oliveira-Paula, Letícia Perticarrara Ferezin, Graziele C. Ferreira, Lucas C. Pinheiro, Jose E. Tanus-Santos, Luis V. Garcia, Riccardo Lacchini, Waynice N. Paula-Garcia
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Current Issues in Molecular Biology
Subjects:
propofol
TRPA1
adverse drug reactions
blood pressure
genetic polymorphisms
nitric oxide
Online Access:https://www.mdpi.com/1467-3045/44/12/432

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