Clinical outcome and humoral immune responses of β-thalassemia major patients with severe iron overload to SARS-CoV-2 infection and vaccination: a prospective cohort studyResearch in context

Clinical outcome and humoral immune responses of β-thalassemia major patients with severe iron overload to SARS-CoV-2 infection and vaccination: a prospective cohort studyResearch in context

Summary: Background: COVID-19 has raised special concern for patients with β-thalassemia major (β-TM) due to frequent comorbidities, regular blood transfusions, and iron overload. However, the exact implications of COVID-19 for patients with β-TM remain uncertain. We aimed to explore the COVID-19 i...

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Bibliographic Details
Main Authors: Hussam Ghoti, Hala Zreid, Israa Ghoti, Arno R. Bourgonje, Arjan Diepstra, Harry van Goor, Irit Avivi, Hisham Jeadi, Larissa E. van Eijk, Günter Weiss
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:EClinicalMedicine
Subjects:
β–thalassemia major
COVID-19
Vaccination
Iron chelation
Splenectomy
Humoral immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023002730

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http://www.sciencedirect.com/science/article/pii/S2589537023002730

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