Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer
Purpose: To evaluate the effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer. Methods: Sixty patients with nasopharyngeal cancer treated with simultaneous integrated boost intensity-modulated radiotherapy were randomly assigned to...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014-06-01
|
| Series: | International Journal of Nursing Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352013214000520 |
| _version_ | 1811217570839134208 |
|---|---|
| author | Juan Xu Rong Yan Pei-Ying Zhuo Ran-Ran Li Hong-Xia Ge Wen-Fang Lu |
| author_facet | Juan Xu Rong Yan Pei-Ying Zhuo Ran-Ran Li Hong-Xia Ge Wen-Fang Lu |
| author_sort | Juan Xu |
| collection | DOAJ |
| description | Purpose: To evaluate the effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer.
Methods: Sixty patients with nasopharyngeal cancer treated with simultaneous integrated boost intensity-modulated radiotherapy were randomly assigned to oxygen nebulization or ultrasonic nebulization groups; treatment was once daily for 20 minutes. All patients received routine oral care. We compared saliva pH and volume, food intake, and change in oral mucosa during radiotherapy, and dry mouth and sore throat after radiotherapy between the two groups.
Results: There were significant differences in the incidence of grade III or IV mucositis, saliva volume and pH, and dry mouth and sore throat between the two groups when the total dose was 33 Gy (p < 0.05 or p < 0.01).
Conclusion: Oxygen nebulization reduces radiotherapy-induced mucositis and relieves symptoms such as dry mouth and sore throat in patients with nasopharyngeal cancer. |
| first_indexed | 2024-04-12T06:57:02Z |
| format | Article |
| id | doaj.art-55f950a8f0e04f319eaf1fcada3ecfc7 |
| institution | Directory Open Access Journal |
| issn | 2352-0132 |
| language | English |
| last_indexed | 2024-04-12T06:57:02Z |
| publishDate | 2014-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Nursing Sciences |
| spelling | doaj.art-55f950a8f0e04f319eaf1fcada3ecfc72022-12-22T03:43:06ZengElsevierInternational Journal of Nursing Sciences2352-01322014-06-011217617910.1016/j.ijnss.2014.05.017Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancerJuan XuRong YanPei-Ying ZhuoRan-Ran LiHong-Xia GeWen-Fang LuPurpose: To evaluate the effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer. Methods: Sixty patients with nasopharyngeal cancer treated with simultaneous integrated boost intensity-modulated radiotherapy were randomly assigned to oxygen nebulization or ultrasonic nebulization groups; treatment was once daily for 20 minutes. All patients received routine oral care. We compared saliva pH and volume, food intake, and change in oral mucosa during radiotherapy, and dry mouth and sore throat after radiotherapy between the two groups. Results: There were significant differences in the incidence of grade III or IV mucositis, saliva volume and pH, and dry mouth and sore throat between the two groups when the total dose was 33 Gy (p < 0.05 or p < 0.01). Conclusion: Oxygen nebulization reduces radiotherapy-induced mucositis and relieves symptoms such as dry mouth and sore throat in patients with nasopharyngeal cancer.http://www.sciencedirect.com/science/article/pii/S2352013214000520Mouth mucosaOxygen atomization inhalationRadiotherapyRadiation injuries |
| spellingShingle | Juan Xu Rong Yan Pei-Ying Zhuo Ran-Ran Li Hong-Xia Ge Wen-Fang Lu Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer International Journal of Nursing Sciences Mouth mucosa Oxygen atomization inhalation Radiotherapy Radiation injuries |
| title | Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer |
| title_full | Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer |
| title_fullStr | Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer |
| title_full_unstemmed | Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer |
| title_short | Effectiveness of oxygen nebulization at preventing radiotherapy-induced mucositis in patients with nasopharyngeal cancer |
| title_sort | effectiveness of oxygen nebulization at preventing radiotherapy induced mucositis in patients with nasopharyngeal cancer |
| topic | Mouth mucosa Oxygen atomization inhalation Radiotherapy Radiation injuries |
| url | http://www.sciencedirect.com/science/article/pii/S2352013214000520 |
| work_keys_str_mv | AT juanxu effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer AT rongyan effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer AT peiyingzhuo effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer AT ranranli effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer AT hongxiage effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer AT wenfanglu effectivenessofoxygennebulizationatpreventingradiotherapyinducedmucositisinpatientswithnasopharyngealcancer |