Pioglitazone enhances cisplatin’s impact on triple-negative breast cancer: Role of PPARγ in cell apoptosis

Pioglitazone enhances cisplatin’s impact on triple-negative breast cancer: Role of PPARγ in cell apoptosis

Peroxisome proliferator-activated receptor-gamma (PPARγ) has been recently shown to play a role in many cancers. The breast tissue of triple-negative breast cancer (TNBC) patients were found to have a significantly lower expression of PPARγ than the other subtypes. Furthermore, PPARγ activation was...

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Bibliographic Details
Main Authors: Qamraa Hamad Alqahtani, Layla Abdullah Alkharashi, Hanaa Alajami, Ishraq Alkharashi, Layan Alkharashi, Shoug Nasser Alhinti
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
Pioglitazone
Cisplatin
Triple-negative breast cancer
PPARγ
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424001099

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