Analysis of Immune–Stromal Score-Based Gene Signature and Molecular Subtypes in Osteosarcoma: Implications for Prognosis and Tumor Immune Microenvironment

Analysis of Immune–Stromal Score-Based Gene Signature and Molecular Subtypes in Osteosarcoma: Implications for Prognosis and Tumor Immune Microenvironment

Objective: Infiltrating immune and stromal cells are essential for osteosarcoma progression. This study set out to analyze immune–stromal score-based gene signature and molecular subtypes in osteosarcoma.Methods: The immune and stromal scores of osteosarcoma specimens from the TARGET cohort were det...

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Bibliographic Details
Main Authors: Dingzhao Zheng, Kaichun Yang, Xinjiang Chen, Yongwu Li, Yongchun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
osteosarcoma
immune score
stromal score
gene signature
prognosis
molecular subtype
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.699385/full

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