Molecular targets in cancer therapy: the Ron approach
The receptor tyrosine kinase Ron and its ligand, Macrophage Stimulating Protein (MSP), mediate multiple processes involved in the control of cell proliferation, migration and protection from apoptosis. Dysregulated signaling of Ron, due to hyperactivation or loss of negative regulation, is involved...
Main Authors: | Serena Germano, Giovanni Gaudino |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-12-01
|
Series: | Oncology Reviews |
Subjects: | |
Online Access: | http://www.oncologyreviews.org/index.php/or/article/view/158 |
Similar Items
-
Molecular targets in cancer therapy: the Ron approach
by: Serena Germano, et al.
Published: (2011-12-01) -
Aberrant RON and MET Co-overexpression as Novel Prognostic Biomarkers of Shortened Patient Survival and Therapeutic Targets of Tyrosine Kinase Inhibitors in Pancreatic Cancer
by: Chen-Yu Hu, et al.
Published: (2019-12-01) -
Splice variants of the extracellular region of RON receptor tyrosine kinase in lung cancer cell lines identified by PCR and sequencing
by: Soundararajan Krishnaswamy, et al.
Published: (2017-11-01) -
EGFR transactivates RON to drive oncogenic crosstalk
by: Carolina Franco Nitta, et al.
Published: (2021-11-01) -
The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies
by: Alex Cazes, et al.
Published: (2022-04-01)