Development and Testing of Monoclonal Antibodies-Based Diagnostic Preparation for <i>Bacillus anthracis</i> Spores Detection Using Latex Agglutination Method

Development and Testing of Monoclonal Antibodies-Based Diagnostic Preparation for <i>Bacillus anthracis</i> Spores Detection Using Latex Agglutination Method

Immobilization of anti-B. anthracis monoclonal antibodies (MAbs) on latex microparticles was studied, the optimal load of these MAbs was determined to be 20 µg for 50 µl of the stock latex suspension. The highest sensitivity of latex agglutination test was observed for 1E6 MAbs. Latex suspensions wi...

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Bibliographic Details
Main Authors: A. E. Khlyntseva, N. M. Luneva, E. V. Belova, I. A. Dyatlov, I. G. Shemyakin
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2011-08-01
Series:Проблемы особо опасных инфекций
Subjects:
monoclonal antibodies (mabs)
latex microparticles
latex agglutination test
sensitivity
specificity
commission tests
Online Access:https://journal.microbe.ru/jour/article/view/709

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