Dynamic observations of CRISPR-Cas target recognition and cleavage heterogeneities

Dynamic observations of CRISPR-Cas target recognition and cleavage heterogeneities

CRISPR-Cas systems (clustered regularly interspaced short palindromic repeats) have shown great potential as efficient gene editing tools in disease therapeutics. Although numerous CRISPR-Cas systems have been developed, detailed mechanisms of target recognition and DNA cleavage are still unclear. I...

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Bibliographic Details
Main Authors: Zhang Zhijia, Jeong Haechan, Zu Di, Zhao Xintao, Senaratne Pramith, Filbin John, Silber Brett, Kang Sarah, Gladstone Ann, Lau Matthew, Cui Guangjie, Park Younggeun, Lee Somin Eunice
Format: Article
Language:English
Published: De Gruyter 2022-08-01
Series:Nanophotonics
Subjects:
bioplasmonics
cas
clustered regularly interspaced short palindromic repeats
gene editing
gold nanorod
plasmonics
sgrna
Online Access:https://doi.org/10.1515/nanoph-2022-0286

Internet

https://doi.org/10.1515/nanoph-2022-0286

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