Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression
This study evaluates whether three definitions of rural and urban residence predict prostate cancer progression. People were classified as urban or rural using three definitions: rural and small town (RST), Beale's rural-urban continuum codes, and the Rurality Index of Ontario (RIO) 2008 score...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Laurentian University Library & Archives
2017-06-01
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| Series: | Diversity of Research in Health Journal |
| Subjects: | |
| Online Access: | https://pubs.biblio.laurentian.ca/index.php/drhj-rdrs/article/view/25 |
| _version_ | 1818324965296963584 |
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| author | Nancy Lightfoot Bruce Oddson Colin Berriault Robert Lafrenie Jacques Abourbih John Macdonald Roger Strasser |
| author_facet | Nancy Lightfoot Bruce Oddson Colin Berriault Robert Lafrenie Jacques Abourbih John Macdonald Roger Strasser |
| author_sort | Nancy Lightfoot |
| collection | DOAJ |
| description | This study evaluates whether three definitions of rural and urban residence predict prostate cancer progression. People were classified as urban or rural using three definitions: rural and small town (RST), Beale's rural-urban continuum codes, and the Rurality Index of Ontario (RIO) 2008 score. This was a chart-based cohort study of males with prostate cancer who underwent external beam radiation therapy (EBRT) in the Regional Cancer Program at Health Sciences North in Sudbury, Ontario from 1996 to 2003. Data indicative of each of the three definitions were used as predictors in Cox regression analysis for the period of 1,000 to 3,000 days after initial diagnosis and as the basis for dichotomous strata in a log rank test.
Complete data were acquired from 629 charts. There was no significant association between any of the three definitions of rurality and prostate cancer progression. However, a Beale-based dichotomization led to survival differences using the log rank test. Beale stratification was potentially sensitive to relevant differences in populations that were not represented by the other two definitions. Given the moderate correlations between the different rurality scores, there may be merit to considering multiple rurality scores as they may lead to different cancer progression outcomes in some situations. |
| first_indexed | 2024-12-13T11:36:58Z |
| format | Article |
| id | doaj.art-561d6cc274624cdb9412bad2ccc6e194 |
| institution | Directory Open Access Journal |
| issn | 2561-1666 |
| language | English |
| last_indexed | 2024-12-13T11:36:58Z |
| publishDate | 2017-06-01 |
| publisher | Laurentian University Library & Archives |
| record_format | Article |
| series | Diversity of Research in Health Journal |
| spelling | doaj.art-561d6cc274624cdb9412bad2ccc6e1942022-12-21T23:47:45ZengLaurentian University Library & ArchivesDiversity of Research in Health Journal2561-16662017-06-01111610.28984/drhj.v1i0.2525Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progressionNancy Lightfoot0Bruce Oddson1Colin Berriault2Robert Lafrenie3Jacques Abourbih4John Macdonald5Roger Strasser6Laurentian UniversityLaurentian UniversityCancer Care OntarioNorthern Ontario School of MedicineNorthern Ontario School of MedicineLaurentian UniversityNorthern Ontario School of MedicineThis study evaluates whether three definitions of rural and urban residence predict prostate cancer progression. People were classified as urban or rural using three definitions: rural and small town (RST), Beale's rural-urban continuum codes, and the Rurality Index of Ontario (RIO) 2008 score. This was a chart-based cohort study of males with prostate cancer who underwent external beam radiation therapy (EBRT) in the Regional Cancer Program at Health Sciences North in Sudbury, Ontario from 1996 to 2003. Data indicative of each of the three definitions were used as predictors in Cox regression analysis for the period of 1,000 to 3,000 days after initial diagnosis and as the basis for dichotomous strata in a log rank test. Complete data were acquired from 629 charts. There was no significant association between any of the three definitions of rurality and prostate cancer progression. However, a Beale-based dichotomization led to survival differences using the log rank test. Beale stratification was potentially sensitive to relevant differences in populations that were not represented by the other two definitions. Given the moderate correlations between the different rurality scores, there may be merit to considering multiple rurality scores as they may lead to different cancer progression outcomes in some situations.https://pubs.biblio.laurentian.ca/index.php/drhj-rdrs/article/view/25prostate cancerprogressionpredictorsdefinitions of rurality |
| spellingShingle | Nancy Lightfoot Bruce Oddson Colin Berriault Robert Lafrenie Jacques Abourbih John Macdonald Roger Strasser Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression Diversity of Research in Health Journal prostate cancer progression predictors definitions of rurality |
| title | Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| title_full | Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| title_fullStr | Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| title_full_unstemmed | Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| title_short | Evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| title_sort | evaluation of the impact of various definitions of rurality on the prediction of prostate cancer progression |
| topic | prostate cancer progression predictors definitions of rurality |
| url | https://pubs.biblio.laurentian.ca/index.php/drhj-rdrs/article/view/25 |
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