Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients

Glaucoma is one of the most common reasons for blindness worldwide, especially in elderly people. Glaucoma can be monitored using visual field (VF) tests. Therefore, predicting the future VF to monitor progression of glaucoma is important. In this paper, we proposed a deep learning model to predict...

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Main Authors: Quang T. M. Pham, Jong Chul Han, Do Young Park, Jitae Shin
Format: Article
Language:English
Published: IEEE 2023-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10050537/
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author Quang T. M. Pham
Jong Chul Han
Do Young Park
Jitae Shin
author_facet Quang T. M. Pham
Jong Chul Han
Do Young Park
Jitae Shin
author_sort Quang T. M. Pham
collection DOAJ
description Glaucoma is one of the most common reasons for blindness worldwide, especially in elderly people. Glaucoma can be monitored using visual field (VF) tests. Therefore, predicting the future VF to monitor progression of glaucoma is important. In this paper, we proposed a deep learning model to predict future VF based on previous VF and optical coherence tomography (OCT) images (including thickness map, vertical tomogram, and horizontal tomogram). The image data were analyzed using a ResNet-50 model. Image features and previous VFs were combined, and a long short-term memory (LSTM) network was used to predict future VF. A weighted method was used to detect noisy data. The proposed method was improved when applying weighted loss. The mean absolute error (MAE) was 3.31 ± 1.37, and the root mean square error (RMSE) was 4.58 ± 1.77. The model showed high performance when combining VF data and OCT image data. Furthermore, the model was useful for detecting and re-weighting noisy data.
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spelling doaj.art-561e507f103b4adaae27dd24df3e84232023-03-02T00:00:38ZengIEEEIEEE Access2169-35362023-01-0111190491905810.1109/ACCESS.2023.324806510050537Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma PatientsQuang T. M. Pham0https://orcid.org/0000-0003-1652-299XJong Chul Han1Do Young Park2https://orcid.org/0000-0001-6089-6898Jitae Shin3https://orcid.org/0000-0002-2599-3331Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon, Republic of KoreaDepartment of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Republic of KoreaDepartment of Electrical and Computer Engineering, Sungkyunkwan University, Suwon, Republic of KoreaGlaucoma is one of the most common reasons for blindness worldwide, especially in elderly people. Glaucoma can be monitored using visual field (VF) tests. Therefore, predicting the future VF to monitor progression of glaucoma is important. In this paper, we proposed a deep learning model to predict future VF based on previous VF and optical coherence tomography (OCT) images (including thickness map, vertical tomogram, and horizontal tomogram). The image data were analyzed using a ResNet-50 model. Image features and previous VFs were combined, and a long short-term memory (LSTM) network was used to predict future VF. A weighted method was used to detect noisy data. The proposed method was improved when applying weighted loss. The mean absolute error (MAE) was 3.31 ± 1.37, and the root mean square error (RMSE) was 4.58 ± 1.77. The model showed high performance when combining VF data and OCT image data. Furthermore, the model was useful for detecting and re-weighting noisy data.https://ieeexplore.ieee.org/document/10050537/Deep learningglaucomaOCTvisual field
spellingShingle Quang T. M. Pham
Jong Chul Han
Do Young Park
Jitae Shin
Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
IEEE Access
Deep learning
glaucoma
OCT
visual field
title Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
title_full Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
title_fullStr Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
title_full_unstemmed Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
title_short Multimodal Deep Learning Model of Predicting Future Visual Field for Glaucoma Patients
title_sort multimodal deep learning model of predicting future visual field for glaucoma patients
topic Deep learning
glaucoma
OCT
visual field
url https://ieeexplore.ieee.org/document/10050537/
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AT jongchulhan multimodaldeeplearningmodelofpredictingfuturevisualfieldforglaucomapatients
AT doyoungpark multimodaldeeplearningmodelofpredictingfuturevisualfieldforglaucomapatients
AT jitaeshin multimodaldeeplearningmodelofpredictingfuturevisualfieldforglaucomapatients