Altered Structural Covariance of Insula, Cerebellum and Prefrontal Cortex Is Associated with Somatic Symptom Levels in Irritable Bowel Syndrome (IBS)

Altered Structural Covariance of Insula, Cerebellum and Prefrontal Cortex Is Associated with Somatic Symptom Levels in Irritable Bowel Syndrome (IBS)

Somatization, defined as the presence of multiple somatic symptoms, frequently occurs in irritable bowel syndrome (IBS) and may constitute the clinical manifestation of a neurobiological sensitization process. Brain imaging data was acquired with T1 weighted 3 tesla MRI, and gray matter morphometry...

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Bibliographic Details
Main Authors: Cecilia Grinsvall, Lukas Van Oudenhove, Patrick Dupont, Hyo Jin Ryu, Maria Ljungberg, Jennifer S. Labus, Hans Törnblom, Emeran A. Mayer, Magnus Simrén
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Brain Sciences
Subjects:
irritable bowel syndrome
somatization
central sensitization
brain morphometry
structural covariance
brain imaging
Online Access:https://www.mdpi.com/2076-3425/11/12/1580

Internet

https://www.mdpi.com/2076-3425/11/12/1580

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