COVID-19 healthcare demand projections: Arizona.

Beginning in March 2020, the United States emerged as the global epicenter for COVID-19 cases with little to guide policy response in the absence of extensive data available for reliable epidemiological modeling in the early phases of the pandemic. In the ensuing weeks, American jurisdictions attemp...

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Main Authors: Esma S Gel, Megan Jehn, Timothy Lant, Anna R Muldoon, Trisalyn Nelson, Heather M Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242588
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author Esma S Gel
Megan Jehn
Timothy Lant
Anna R Muldoon
Trisalyn Nelson
Heather M Ross
author_facet Esma S Gel
Megan Jehn
Timothy Lant
Anna R Muldoon
Trisalyn Nelson
Heather M Ross
author_sort Esma S Gel
collection DOAJ
description Beginning in March 2020, the United States emerged as the global epicenter for COVID-19 cases with little to guide policy response in the absence of extensive data available for reliable epidemiological modeling in the early phases of the pandemic. In the ensuing weeks, American jurisdictions attempted to manage disease spread on a regional basis using non-pharmaceutical interventions (i.e., social distancing), as uneven disease burden across the expansive geography of the United States exerted different implications for policy management in different regions. While Arizona policymakers relied initially on state-by-state national modeling projections from different groups outside of the state, we sought to create a state-specific model using a mathematical framework that ties disease surveillance with the future burden on Arizona's healthcare system. Our framework uses a compartmental system dynamics model using a SEIRD framework that accounts for multiple types of disease manifestations for the COVID-19 infection, as well as the observed time delay in epidemiological findings following public policy enactments. We use a compartment initialization logic coupled with a fitting technique to construct projections for key metrics to guide public health policy, including exposures, infections, hospitalizations, and deaths under a variety of social reopening scenarios. Our approach makes use of X-factor fitting and backcasting methods to construct meaningful and reliable models with minimal available data in order to provide timely policy guidance in the early phases of a pandemic.
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spelling doaj.art-562295ccfa5242cfaffd8b6aae851d382022-12-21T19:39:03ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011512e024258810.1371/journal.pone.0242588COVID-19 healthcare demand projections: Arizona.Esma S GelMegan JehnTimothy LantAnna R MuldoonTrisalyn NelsonHeather M RossBeginning in March 2020, the United States emerged as the global epicenter for COVID-19 cases with little to guide policy response in the absence of extensive data available for reliable epidemiological modeling in the early phases of the pandemic. In the ensuing weeks, American jurisdictions attempted to manage disease spread on a regional basis using non-pharmaceutical interventions (i.e., social distancing), as uneven disease burden across the expansive geography of the United States exerted different implications for policy management in different regions. While Arizona policymakers relied initially on state-by-state national modeling projections from different groups outside of the state, we sought to create a state-specific model using a mathematical framework that ties disease surveillance with the future burden on Arizona's healthcare system. Our framework uses a compartmental system dynamics model using a SEIRD framework that accounts for multiple types of disease manifestations for the COVID-19 infection, as well as the observed time delay in epidemiological findings following public policy enactments. We use a compartment initialization logic coupled with a fitting technique to construct projections for key metrics to guide public health policy, including exposures, infections, hospitalizations, and deaths under a variety of social reopening scenarios. Our approach makes use of X-factor fitting and backcasting methods to construct meaningful and reliable models with minimal available data in order to provide timely policy guidance in the early phases of a pandemic.https://doi.org/10.1371/journal.pone.0242588
spellingShingle Esma S Gel
Megan Jehn
Timothy Lant
Anna R Muldoon
Trisalyn Nelson
Heather M Ross
COVID-19 healthcare demand projections: Arizona.
PLoS ONE
title COVID-19 healthcare demand projections: Arizona.
title_full COVID-19 healthcare demand projections: Arizona.
title_fullStr COVID-19 healthcare demand projections: Arizona.
title_full_unstemmed COVID-19 healthcare demand projections: Arizona.
title_short COVID-19 healthcare demand projections: Arizona.
title_sort covid 19 healthcare demand projections arizona
url https://doi.org/10.1371/journal.pone.0242588
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AT trisalynnelson covid19healthcaredemandprojectionsarizona
AT heathermross covid19healthcaredemandprojectionsarizona