Connexin 43 dephosphorylation at serine 282 induces spontaneous arrhythmia and increases susceptibility to ischemia/reperfusion injury

Connexin 43 dephosphorylation at serine 282 induces spontaneous arrhythmia and increases susceptibility to ischemia/reperfusion injury

Background: Connexin 43 (Cx43), the predominant gap junction protein in hearts, is modified by specific (de)phosphorylation events under physiological and pathological states to affect myocardium function and structure. Previously we found that deficiency in Cx43 S282 phosphorylation could impair in...

Full description

Bibliographic Details
Main Authors: Lulin Wu, Tianhui Jiang, Zhiping Fu, Luqi Wang, Hongjie You, Jingyi Xue, Dali Luo
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Connexin 43
Arrhythmia
Apoptosis
Ischemia/reperfusion
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023030864

Similar Items

Similar Items