The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer

The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer

Abstract The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune res...

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Bibliographic Details
Main Authors: Shuangcui Wang, Guan Zhang, Qian Cui, Yanjie Yang, Dong Wang, Aqing Liu, Ying Xia, Wentao Li, Yunhe Liu, Jianchun Yu
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Immunity, Inflammation and Disease
Subjects:
artificial DCs
chimeric antigen receptor T cell immunotherapy
DCs
NSCLC
T cells
Online Access:https://doi.org/10.1002/iid3.1099
Description
Summary:Abstract The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to non‐small cell lung cancer (NSCLC). In this article, a review was made of the interaction between DCs and T cells in the treatment of NSCLC and how this interaction affects the treatment outcome.
ISSN:2050-4527

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