The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer
Abstract The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune res...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-11-01
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| Series: | Immunity, Inflammation and Disease |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/iid3.1099 |
| _version_ | 1797404109511327744 |
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| author | Shuangcui Wang Guan Zhang Qian Cui Yanjie Yang Dong Wang Aqing Liu Ying Xia Wentao Li Yunhe Liu Jianchun Yu |
| author_facet | Shuangcui Wang Guan Zhang Qian Cui Yanjie Yang Dong Wang Aqing Liu Ying Xia Wentao Li Yunhe Liu Jianchun Yu |
| author_sort | Shuangcui Wang |
| collection | DOAJ |
| description | Abstract The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to non‐small cell lung cancer (NSCLC). In this article, a review was made of the interaction between DCs and T cells in the treatment of NSCLC and how this interaction affects the treatment outcome. |
| first_indexed | 2024-03-09T02:50:13Z |
| format | Article |
| id | doaj.art-5624a61947484442a923cb9f3256c539 |
| institution | Directory Open Access Journal |
| issn | 2050-4527 |
| language | English |
| last_indexed | 2024-03-09T02:50:13Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Immunity, Inflammation and Disease |
| spelling | doaj.art-5624a61947484442a923cb9f3256c5392023-12-05T11:18:02ZengWileyImmunity, Inflammation and Disease2050-45272023-11-011111n/an/a10.1002/iid3.1099The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancerShuangcui Wang0Guan Zhang1Qian Cui2Yanjie Yang3Dong Wang4Aqing Liu5Ying Xia6Wentao Li7Yunhe Liu8Jianchun Yu9Department of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaDepartment of Oncology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin ChinaAbstract The dendritic cell (DC)‐T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen‐presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to non‐small cell lung cancer (NSCLC). In this article, a review was made of the interaction between DCs and T cells in the treatment of NSCLC and how this interaction affects the treatment outcome.https://doi.org/10.1002/iid3.1099artificial DCschimeric antigen receptor T cell immunotherapyDCsNSCLCT cells |
| spellingShingle | Shuangcui Wang Guan Zhang Qian Cui Yanjie Yang Dong Wang Aqing Liu Ying Xia Wentao Li Yunhe Liu Jianchun Yu The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer Immunity, Inflammation and Disease artificial DCs chimeric antigen receptor T cell immunotherapy DCs NSCLC T cells |
| title | The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer |
| title_full | The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer |
| title_fullStr | The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer |
| title_full_unstemmed | The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer |
| title_short | The DC–T cell axis is an effective target for the treatment of non‐small cell lung cancer |
| title_sort | dc t cell axis is an effective target for the treatment of non small cell lung cancer |
| topic | artificial DCs chimeric antigen receptor T cell immunotherapy DCs NSCLC T cells |
| url | https://doi.org/10.1002/iid3.1099 |
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