A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital

Introduction: The shock index (SI), modified shock index (MSI), and age multiplied by SI (ASI) are used to assess the severity of shock. They are also used to predict the mortality of trauma patients, but their validity for sepsis patients is controversial. The aim of this study is to assess the pre...

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Main Authors: K J Devendra Prasad, K C Hima Bindu, T Abhinov, Krishna Moorthy, K Rajesh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Emergencies, Trauma and Shock
Subjects:
Online Access:http://www.onlinejets.org/article.asp?issn=0974-2700;year=2023;volume=16;issue=1;spage=17;epage=21;aulast=Devendra
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author K J Devendra Prasad
K C Hima Bindu
T Abhinov
Krishna Moorthy
K Rajesh
author_facet K J Devendra Prasad
K C Hima Bindu
T Abhinov
Krishna Moorthy
K Rajesh
author_sort K J Devendra Prasad
collection DOAJ
description Introduction: The shock index (SI), modified shock index (MSI), and age multiplied by SI (ASI) are used to assess the severity of shock. They are also used to predict the mortality of trauma patients, but their validity for sepsis patients is controversial. The aim of this study is to assess the predictive value of the SI, MSI, and ASI in predicting the need for mechanical ventilation after 24 h of admission among sepsis patients. Methods: A prospective observational study was conducted in a tertiary care teaching hospital. Patients with sepsis (235) diagnosed based on systemic inflammatory response syndrome criteria and quick sequential organ failure assessment were included in the study. The need for mechanical ventilation after 24 h is the outcome variables MSI, SI, and ASI were considered as predictor variables. The utility of MSI, SI, and ASI in predicting mechanical ventilation was assessed by receiver operative curve analysis. Data were analyzed using coGuide. Results: Among the study population, the mean age was 56.12 ± 17.28 years. MSI value at the time of disposition from the emergency room had good predictive validity in predicting mechanical ventilation after 24 h, as indicated by the area under the curve (AUC) of 0.81 (P < 0.001), SI and ASI had fair predictive validity for mechanical ventilation as indicated by AUC (0.78, P < 0.001) and (0.802, P < 0.001), respectively. Conclusion: SI had better sensitivity (78.57%) and specificity (77.07%) compared to ASI and MSI in predicting the need for mechanical ventilation after 24 h in sepsis patients admitted to intensive care units.
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spelling doaj.art-562501b1650e4b7f883b1bb34502c7ca2023-07-21T11:35:39ZengWolters Kluwer Medknow PublicationsJournal of Emergencies, Trauma and Shock0974-27002023-01-01161172110.4103/jets.jets_118_22A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospitalK J Devendra PrasadK C Hima BinduT AbhinovKrishna MoorthyK RajeshIntroduction: The shock index (SI), modified shock index (MSI), and age multiplied by SI (ASI) are used to assess the severity of shock. They are also used to predict the mortality of trauma patients, but their validity for sepsis patients is controversial. The aim of this study is to assess the predictive value of the SI, MSI, and ASI in predicting the need for mechanical ventilation after 24 h of admission among sepsis patients. Methods: A prospective observational study was conducted in a tertiary care teaching hospital. Patients with sepsis (235) diagnosed based on systemic inflammatory response syndrome criteria and quick sequential organ failure assessment were included in the study. The need for mechanical ventilation after 24 h is the outcome variables MSI, SI, and ASI were considered as predictor variables. The utility of MSI, SI, and ASI in predicting mechanical ventilation was assessed by receiver operative curve analysis. Data were analyzed using coGuide. Results: Among the study population, the mean age was 56.12 ± 17.28 years. MSI value at the time of disposition from the emergency room had good predictive validity in predicting mechanical ventilation after 24 h, as indicated by the area under the curve (AUC) of 0.81 (P < 0.001), SI and ASI had fair predictive validity for mechanical ventilation as indicated by AUC (0.78, P < 0.001) and (0.802, P < 0.001), respectively. Conclusion: SI had better sensitivity (78.57%) and specificity (77.07%) compared to ASI and MSI in predicting the need for mechanical ventilation after 24 h in sepsis patients admitted to intensive care units.http://www.onlinejets.org/article.asp?issn=0974-2700;year=2023;volume=16;issue=1;spage=17;epage=21;aulast=Devendraemergency medical servicesintensive caremechanical ventilationshock
spellingShingle K J Devendra Prasad
K C Hima Bindu
T Abhinov
Krishna Moorthy
K Rajesh
A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
Journal of Emergencies, Trauma and Shock
emergency medical services
intensive care
mechanical ventilation
shock
title A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
title_full A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
title_fullStr A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
title_full_unstemmed A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
title_short A comparative study on predictive validity of modified shock index, shock index, and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
title_sort comparative study on predictive validity of modified shock index shock index and age shock index in predicting the need for mechanical ventilation among sepsis patients in a tertiary care hospital
topic emergency medical services
intensive care
mechanical ventilation
shock
url http://www.onlinejets.org/article.asp?issn=0974-2700;year=2023;volume=16;issue=1;spage=17;epage=21;aulast=Devendra
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