Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report
Abstract Background Pulmonary sarcomatoid carcinoma (PSC) is a rare malignancy with both epithelial and sarcoma components, and high tumor metastasis potential. Case presentation A 63-year-old male patient had a tumor in the right posterior mediastinum, and was eventually diagnosed with PSC and ging...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-09-01
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| Series: | Journal of Cardiothoracic Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13019-019-0991-y |
| _version_ | 1829141647311503360 |
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| author | Zhonghua Qin Bin Huang Guiping Yu Yongqiang Zheng Ke Zhao |
| author_facet | Zhonghua Qin Bin Huang Guiping Yu Yongqiang Zheng Ke Zhao |
| author_sort | Zhonghua Qin |
| collection | DOAJ |
| description | Abstract Background Pulmonary sarcomatoid carcinoma (PSC) is a rare malignancy with both epithelial and sarcoma components, and high tumor metastasis potential. Case presentation A 63-year-old male patient had a tumor in the right posterior mediastinum, and was eventually diagnosed with PSC and gingival metastasis. The patient underwent thoracoscopic right upper pneumonectomy with lymph node dissections, and the subsequent gingival biopsy revealed a metastatic PSC. The immunohistochemistry revealed that both PSC site tissues were positive for vimentin, CKAE1/AE3 and Ki-67. The patient received radiotherapy and chemotherapy after surgery, and deceased two months later due to systemic tumor metastases. Conclusion PSC metastasis is variable, and leads to diagnostic dilemma or erroneous diagnosis. A differential diagnosis can help to distinguish it from gingival cancer. |
| first_indexed | 2024-12-14T20:18:08Z |
| format | Article |
| id | doaj.art-5625d0053c3a4532916bd021954aff78 |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-14T20:18:08Z |
| publishDate | 2019-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-5625d0053c3a4532916bd021954aff782022-12-21T22:48:48ZengBMCJournal of Cardiothoracic Surgery1749-80902019-09-011411410.1186/s13019-019-0991-yGingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case reportZhonghua Qin0Bin Huang1Guiping Yu2Yongqiang Zheng3Ke Zhao4Department of Cardiothoracic Surgery, The affiliated Jiangyin People’s Hospital of Southeast University Medical CollegeDepartment of Cardiothoracic Surgery, The affiliated Jiangyin People’s Hospital of Southeast University Medical CollegeDepartment of Cardiothoracic Surgery, The affiliated Jiangyin People’s Hospital of Southeast University Medical CollegeDepartment of Radiology, The affiliated Jiangyin People’s Hospital of Southeast University Medical CollegeDepartment of Pathology, The affiliated Jiangyin People’s Hospital of Southeast University Medical CollegeAbstract Background Pulmonary sarcomatoid carcinoma (PSC) is a rare malignancy with both epithelial and sarcoma components, and high tumor metastasis potential. Case presentation A 63-year-old male patient had a tumor in the right posterior mediastinum, and was eventually diagnosed with PSC and gingival metastasis. The patient underwent thoracoscopic right upper pneumonectomy with lymph node dissections, and the subsequent gingival biopsy revealed a metastatic PSC. The immunohistochemistry revealed that both PSC site tissues were positive for vimentin, CKAE1/AE3 and Ki-67. The patient received radiotherapy and chemotherapy after surgery, and deceased two months later due to systemic tumor metastases. Conclusion PSC metastasis is variable, and leads to diagnostic dilemma or erroneous diagnosis. A differential diagnosis can help to distinguish it from gingival cancer.http://link.springer.com/article/10.1186/s13019-019-0991-yPulmonary sarcomatoid carcinomaNon-small cell lung cancerGingival tumor metastasisVideo-assisted thoracic surgery |
| spellingShingle | Zhonghua Qin Bin Huang Guiping Yu Yongqiang Zheng Ke Zhao Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report Journal of Cardiothoracic Surgery Pulmonary sarcomatoid carcinoma Non-small cell lung cancer Gingival tumor metastasis Video-assisted thoracic surgery |
| title | Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report |
| title_full | Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report |
| title_fullStr | Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report |
| title_full_unstemmed | Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report |
| title_short | Gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma: a case report |
| title_sort | gingival metastasis of a mediastinal pulmonary sarcomatoid carcinoma a case report |
| topic | Pulmonary sarcomatoid carcinoma Non-small cell lung cancer Gingival tumor metastasis Video-assisted thoracic surgery |
| url | http://link.springer.com/article/10.1186/s13019-019-0991-y |
| work_keys_str_mv | AT zhonghuaqin gingivalmetastasisofamediastinalpulmonarysarcomatoidcarcinomaacasereport AT binhuang gingivalmetastasisofamediastinalpulmonarysarcomatoidcarcinomaacasereport AT guipingyu gingivalmetastasisofamediastinalpulmonarysarcomatoidcarcinomaacasereport AT yongqiangzheng gingivalmetastasisofamediastinalpulmonarysarcomatoidcarcinomaacasereport AT kezhao gingivalmetastasisofamediastinalpulmonarysarcomatoidcarcinomaacasereport |