Beneficial effects of intravenous iron therapy in a rat model of heart failure with preserved systemic iron status but depleted intracellular cardiac stores

Beneficial effects of intravenous iron therapy in a rat model of heart failure with preserved systemic iron status but depleted intracellular cardiac stores

Abstract Iron deficiency (ID) commonly occurs in chronic heart failure (HF) and is associated with poor prognosis. Neither its causes nor pathophysiological significance are clearly understood. We aimed to assess iron status and the effect of iron supplementation in the rat model of post-myocardial...

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Bibliographic Details
Main Authors: Aleksandra Paterek, Marta Kępska, Barbara Sochanowicz, Ewelina Chajduk, Joanna Kołodziejczyk, Halina Polkowska-Motrenko, Marcin Kruszewski, Przemysław Leszek, Urszula Mackiewicz, Michał Mączewski
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Scientific Reports
Subjects:
Systemic Iron Status
Ferric Carboxymaltose
Intravenous Iron Supplementation
Sarcoplasmic Reticulum (SR) Ca2+-ATPase (SERCA)
Myocardial Iron Content
Online Access:https://doi.org/10.1038/s41598-018-33277-2

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