Bioinformatic Analysis of Kynurenine Pathway Enzymes and Their Relationship with Glioma Hallmarks

Bioinformatic Analysis of Kynurenine Pathway Enzymes and Their Relationship with Glioma Hallmarks

Indoleamine dioxygenase (IDO), a rate limiting enzyme of the tryptophan catabolism through the kynurenine pathway (KP), has been related with a lower survival and a poor patient prognosis on several solid tumors, including gliomas. However, the use of IDO inhibitors as a therapeutic strategy for tum...

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Bibliographic Details
Main Authors: Gustavo Ignacio Vázquez Cervantes, Javier Ángel Navarro Cossio, Gonzalo Pérez de la Cruz, Aleli Salazar, Verónica Pérez de la Cruz, Benjamin Pineda
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
tryptophan catabolism
glioma
immune response
Online Access:https://www.mdpi.com/2218-1989/12/11/1054

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