Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report
IntroductionA rare pathogen of Infective Endocarditis (IE), the Abiotrophia defectiva, has been known to trigger life-threatening complications. The case discussed here is of a teenager with brain infarction and subarachnoid hemorrhage caused by IE due to A. defectiva.Case reportA 15-year-old girl w...
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1117474/full |
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| author | Miaojuan Yang Miaojuan Yang Miaojuan Yang Yanxia Lin Xin Peng Jingsong Wu Bo Hu Bo Hu Bo Hu Yitao He Yitao He Yitao He Jian Lu |
| author_facet | Miaojuan Yang Miaojuan Yang Miaojuan Yang Yanxia Lin Xin Peng Jingsong Wu Bo Hu Bo Hu Bo Hu Yitao He Yitao He Yitao He Jian Lu |
| author_sort | Miaojuan Yang |
| collection | DOAJ |
| description | IntroductionA rare pathogen of Infective Endocarditis (IE), the Abiotrophia defectiva, has been known to trigger life-threatening complications. The case discussed here is of a teenager with brain infarction and subarachnoid hemorrhage caused by IE due to A. defectiva.Case reportA 15-year-old girl with movement disorders involving the left limbs and intermittent fevers was admitted to the hospital. A head CT scan revealed cerebral infarction in the right basal ganglia and subarachnoid hemorrhage. Moreover, vegetation on the mitral valve were confirmed by echocardiography. The blood cultures were found to be positive for Gram-positive streptococcus and identified by Vitek mass spectrometry as A. defectiva. She was prescribed vancomycin antibacterial therapy and underwent a surgical mitral valve replacement.ConclusionThis case is suggestive of the fact that A. defectiva is a rare but crucial pathogen of IE-associated stroke. Obtaining early blood cultures and using microbial mass spectrometry could help achieve an accurate diagnosis. Moreover, reasonable anti-infective medications and surgical interventions need to be combined to avoid and/or manage severe complications. |
| first_indexed | 2024-04-09T14:42:15Z |
| format | Article |
| id | doaj.art-563d30d9cddc4e08a2ea5a0d70072904 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-09T14:42:15Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-563d30d9cddc4e08a2ea5a0d700729042023-05-03T04:45:43ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-05-011010.3389/fmed.2023.11174741117474Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case reportMiaojuan Yang0Miaojuan Yang1Miaojuan Yang2Yanxia Lin3Xin Peng4Jingsong Wu5Bo Hu6Bo Hu7Bo Hu8Yitao He9Yitao He10Yitao He11Jian Lu12Department of Neurology, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, ChinaThe First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, ChinaShenzhen Clinical Research Center for Geriatrics, Shenzhen People's Hospital, Shenzhen, ChinaDepartment of Infectious Diseases, Shenzhen University General Hospital, Shenzhen, ChinaDepartment of Cardiology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, Guangdong, ChinaDepartment of Laboratory Medicine, Shenzhen People's Hospital, Shenzhen, ChinaDepartment of Neurology, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, ChinaThe First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, ChinaShenzhen Clinical Research Center for Geriatrics, Shenzhen People's Hospital, Shenzhen, ChinaDepartment of Neurology, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, ChinaThe First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong, ChinaShenzhen Clinical Research Center for Geriatrics, Shenzhen People's Hospital, Shenzhen, ChinaDepartment of Infectious Diseases, Shenzhen University General Hospital, Shenzhen, ChinaIntroductionA rare pathogen of Infective Endocarditis (IE), the Abiotrophia defectiva, has been known to trigger life-threatening complications. The case discussed here is of a teenager with brain infarction and subarachnoid hemorrhage caused by IE due to A. defectiva.Case reportA 15-year-old girl with movement disorders involving the left limbs and intermittent fevers was admitted to the hospital. A head CT scan revealed cerebral infarction in the right basal ganglia and subarachnoid hemorrhage. Moreover, vegetation on the mitral valve were confirmed by echocardiography. The blood cultures were found to be positive for Gram-positive streptococcus and identified by Vitek mass spectrometry as A. defectiva. She was prescribed vancomycin antibacterial therapy and underwent a surgical mitral valve replacement.ConclusionThis case is suggestive of the fact that A. defectiva is a rare but crucial pathogen of IE-associated stroke. Obtaining early blood cultures and using microbial mass spectrometry could help achieve an accurate diagnosis. Moreover, reasonable anti-infective medications and surgical interventions need to be combined to avoid and/or manage severe complications.https://www.frontiersin.org/articles/10.3389/fmed.2023.1117474/fullAbiotrophia defectivainfective endocarditisbrain infarctionsubarachnoid hemorrhagemicrobial mass spectrometry |
| spellingShingle | Miaojuan Yang Miaojuan Yang Miaojuan Yang Yanxia Lin Xin Peng Jingsong Wu Bo Hu Bo Hu Bo Hu Yitao He Yitao He Yitao He Jian Lu Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report Frontiers in Medicine Abiotrophia defectiva infective endocarditis brain infarction subarachnoid hemorrhage microbial mass spectrometry |
| title | Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report |
| title_full | Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report |
| title_fullStr | Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report |
| title_full_unstemmed | Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report |
| title_short | Abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage: a case report |
| title_sort | abiotrophia defectiva causing infective endocarditis with brain infarction and subarachnoid hemorrhage a case report |
| topic | Abiotrophia defectiva infective endocarditis brain infarction subarachnoid hemorrhage microbial mass spectrometry |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1117474/full |
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