Structural basis for the regulation of maternal embryonic leucine zipper kinase.

Structural basis for the regulation of maternal embryonic leucine zipper kinase.

MELK (maternal embryonic leucine zipper kinase), which is a member of the AMPK (AMP-activated protein kinase)-related kinase family, plays important roles in diverse cellular processes and has become a promising drug target for certain cancers. However, the regulatory mechanism of MELK remains elusi...

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Bibliographic Details
Main Authors: Lu-Sha Cao, Jue Wang, Yuling Chen, Haiteng Deng, Zhi-Xin Wang, Jia-Wei Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724675?pdf=render

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