Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis
Dementia is an important health issue worldwide, and non-pharmacological strategies for the management of behavioral and psychological symptoms of dementia (BPSD) are considered to be important. This review analyzes the effectiveness and safety of acupuncture for BPSD. Thirteen electronic databases...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/14/3087 |
| _version_ | 1797526854249218048 |
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| author | Chan-Young Kwon Boram Lee |
| author_facet | Chan-Young Kwon Boram Lee |
| author_sort | Chan-Young Kwon |
| collection | DOAJ |
| description | Dementia is an important health issue worldwide, and non-pharmacological strategies for the management of behavioral and psychological symptoms of dementia (BPSD) are considered to be important. This review analyzes the effectiveness and safety of acupuncture for BPSD. Thirteen electronic databases were comprehensively searched to find clinical studies using acupuncture on BPSD, published up to December 2020. Five randomized controlled clinical trials and two before-after studies, mainly on Alzheimer’s disease (AD), were included. Meta-analysis suggested that the total effective rate based on BPSD symptoms in the acupuncture combined with psychotropic drugs group was significantly higher than that in the psychotropic drugs group (risk ratio, 1.27; 95% confidence interval, 1.11 to 1.45; I<sup>2</sup> = 51%). In terms of other outcomes related to BPSD, acupuncture as an adjunctive therapy, but not as monotherapy, was associated with significant benefits in most included studies. However, the included studies did not have optimal methodological quality. Our review highlights the limited evidence proving the effectiveness and safety of acupuncture for BPSD in patients with AD. Although some clinical studies have reported the potential benefits of adjuvant acupuncture in managing BPSD, the evidence is not robust and is based on small studies. Therefore, high-quality research in this field is needed. |
| first_indexed | 2024-03-10T09:35:17Z |
| format | Article |
| id | doaj.art-5641ac78e7684fc28ad9e2dd6feb1004 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T09:35:17Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-5641ac78e7684fc28ad9e2dd6feb10042023-11-22T04:06:32ZengMDPI AGJournal of Clinical Medicine2077-03832021-07-011014308710.3390/jcm10143087Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-AnalysisChan-Young Kwon0Boram Lee1Department of Oriental Neuropsychiatry, Dong-eui University College of Korean Medicine, 52-57 Yangjeong-ro, Busanjin-gu, Busan 47227, KoreaDepartment of Clinical Korean Medicine, Graduate School, Kyung Hee University, 26 Kyunghee-daero, Dongdaemun-gu, Seoul 02447, KoreaDementia is an important health issue worldwide, and non-pharmacological strategies for the management of behavioral and psychological symptoms of dementia (BPSD) are considered to be important. This review analyzes the effectiveness and safety of acupuncture for BPSD. Thirteen electronic databases were comprehensively searched to find clinical studies using acupuncture on BPSD, published up to December 2020. Five randomized controlled clinical trials and two before-after studies, mainly on Alzheimer’s disease (AD), were included. Meta-analysis suggested that the total effective rate based on BPSD symptoms in the acupuncture combined with psychotropic drugs group was significantly higher than that in the psychotropic drugs group (risk ratio, 1.27; 95% confidence interval, 1.11 to 1.45; I<sup>2</sup> = 51%). In terms of other outcomes related to BPSD, acupuncture as an adjunctive therapy, but not as monotherapy, was associated with significant benefits in most included studies. However, the included studies did not have optimal methodological quality. Our review highlights the limited evidence proving the effectiveness and safety of acupuncture for BPSD in patients with AD. Although some clinical studies have reported the potential benefits of adjuvant acupuncture in managing BPSD, the evidence is not robust and is based on small studies. Therefore, high-quality research in this field is needed.https://www.mdpi.com/2077-0383/10/14/3087dementiaBPSDacupuncture therapyacupuncturesystematic review |
| spellingShingle | Chan-Young Kwon Boram Lee Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis Journal of Clinical Medicine dementia BPSD acupuncture therapy acupuncture systematic review |
| title | Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis |
| title_full | Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis |
| title_fullStr | Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis |
| title_short | Acupuncture for Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis |
| title_sort | acupuncture for behavioral and psychological symptoms of dementia a systematic review and meta analysis |
| topic | dementia BPSD acupuncture therapy acupuncture systematic review |
| url | https://www.mdpi.com/2077-0383/10/14/3087 |
| work_keys_str_mv | AT chanyoungkwon acupunctureforbehavioralandpsychologicalsymptomsofdementiaasystematicreviewandmetaanalysis AT boramlee acupunctureforbehavioralandpsychologicalsymptomsofdementiaasystematicreviewandmetaanalysis |