Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery
Abstract Background The aim of this study was to evaluate the safety and effectiveness of robot‐assisted thymectomy (RAT) in large anterior mediastinal tumors (AMTs) (size ≥6 cm) compared with video‐assisted thymectomy (VAT) and open surgery. Methods A total of 132 patients with large AMTs who under...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.14744 |
| _version_ | 1797945038684028928 |
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| author | Bin Jiang Qun‐You Tan Bo Deng Long‐Yong Mei Yi‐Dan Lin Long‐Fei Zhu |
| author_facet | Bin Jiang Qun‐You Tan Bo Deng Long‐Yong Mei Yi‐Dan Lin Long‐Fei Zhu |
| author_sort | Bin Jiang |
| collection | DOAJ |
| description | Abstract Background The aim of this study was to evaluate the safety and effectiveness of robot‐assisted thymectomy (RAT) in large anterior mediastinal tumors (AMTs) (size ≥6 cm) compared with video‐assisted thymectomy (VAT) and open surgery. Methods A total of 132 patients with large AMTs who underwent surgical resection from January 2016 to June 2022 were included in this study. A total of 61 patients underwent RAT, 36 patients underwent VAT and 35 patients underwent open surgery. Perioperative outcomes were compared. Results There were no significant differences in tumor size (p = 0.141), or pathological types (p = 0.903). Compared with the open group, the RAT and VAT groups were associated with a shorter operation time (115.00 vs. 160.00, p = 0.012; 122.50 vs. 160.00, p = 0.071), and less blood loss (50.00 vs. 200.00, p < 0.001; 50.00 vs. 200.00, p < 0.001), respectively. The rate of conversion in the RAT group was similar to that in the VAT group (6.56% vs. 13.89%, p = 0.229). Concomitant resection was less frequently performed in the VAT group than in the RAT and open groups (5.56% vs. 31.15%, p = 0.040; 5.56% vs. 31.43%, p = 0.006). VAT patients had a lower drainage volume (365.00 vs. 700.00 and 910.00 mL, p < 0.001), shorter duration of chest tube (2.00 vs. 3.00 and 4.00, p < 0.001), and shorter hospital stay (5.00 vs. 6.00 and 7.00, p < 0.001) than the RAT and open groups. There was no 30‐day mortality in any group. No difference was seen in R0 resection rates (p = 0.846). The postoperative complication rates were similar among the three groups (p = 0.309). Total in‐hospital costs (66493.90 vs. 33581.05 and 42876.40, p < 0.001) were significantly higher in the RAT group. Conclusions RAT is safe and effective for the resection of large AMTs compared to VAT and open surgery. Vascular resection in RAT is technically feasible. A long‐term follow‐up is required. |
| first_indexed | 2024-04-10T20:47:55Z |
| format | Article |
| id | doaj.art-56424b3410934899afc176cd9afbc8c0 |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-04-10T20:47:55Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-56424b3410934899afc176cd9afbc8c02023-01-24T01:23:12ZengWileyThoracic Cancer1759-77061759-77142023-01-0114326727310.1111/1759-7714.14744Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgeryBin Jiang0Qun‐You Tan1Bo Deng2Long‐Yong Mei3Yi‐Dan Lin4Long‐Fei Zhu5Department of Thoracic Surgery West China Hospital, Sichuan University Chengdu ChinaDepartment of Thoracic Surgery, Daping Hospital (Army Medical Center of Chinese People's Liberation Army) Army Medical University Chongqing ChinaDepartment of Thoracic Surgery, Daping Hospital (Army Medical Center of Chinese People's Liberation Army) Army Medical University Chongqing ChinaDepartment of Thoracic Surgery, Daping Hospital (Army Medical Center of Chinese People's Liberation Army) Army Medical University Chongqing ChinaDepartment of Thoracic Surgery West China Hospital, Sichuan University Chengdu ChinaDepartment of Thoracic Surgery, Daping Hospital (Army Medical Center of Chinese People's Liberation Army) Army Medical University Chongqing ChinaAbstract Background The aim of this study was to evaluate the safety and effectiveness of robot‐assisted thymectomy (RAT) in large anterior mediastinal tumors (AMTs) (size ≥6 cm) compared with video‐assisted thymectomy (VAT) and open surgery. Methods A total of 132 patients with large AMTs who underwent surgical resection from January 2016 to June 2022 were included in this study. A total of 61 patients underwent RAT, 36 patients underwent VAT and 35 patients underwent open surgery. Perioperative outcomes were compared. Results There were no significant differences in tumor size (p = 0.141), or pathological types (p = 0.903). Compared with the open group, the RAT and VAT groups were associated with a shorter operation time (115.00 vs. 160.00, p = 0.012; 122.50 vs. 160.00, p = 0.071), and less blood loss (50.00 vs. 200.00, p < 0.001; 50.00 vs. 200.00, p < 0.001), respectively. The rate of conversion in the RAT group was similar to that in the VAT group (6.56% vs. 13.89%, p = 0.229). Concomitant resection was less frequently performed in the VAT group than in the RAT and open groups (5.56% vs. 31.15%, p = 0.040; 5.56% vs. 31.43%, p = 0.006). VAT patients had a lower drainage volume (365.00 vs. 700.00 and 910.00 mL, p < 0.001), shorter duration of chest tube (2.00 vs. 3.00 and 4.00, p < 0.001), and shorter hospital stay (5.00 vs. 6.00 and 7.00, p < 0.001) than the RAT and open groups. There was no 30‐day mortality in any group. No difference was seen in R0 resection rates (p = 0.846). The postoperative complication rates were similar among the three groups (p = 0.309). Total in‐hospital costs (66493.90 vs. 33581.05 and 42876.40, p < 0.001) were significantly higher in the RAT group. Conclusions RAT is safe and effective for the resection of large AMTs compared to VAT and open surgery. Vascular resection in RAT is technically feasible. A long‐term follow‐up is required.https://doi.org/10.1111/1759-7714.14744anterior mediastinal tumorrobot‐assisted thymectomyvideo‐assisted thymectomy |
| spellingShingle | Bin Jiang Qun‐You Tan Bo Deng Long‐Yong Mei Yi‐Dan Lin Long‐Fei Zhu Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery Thoracic Cancer anterior mediastinal tumor robot‐assisted thymectomy video‐assisted thymectomy |
| title | Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery |
| title_full | Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery |
| title_fullStr | Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery |
| title_full_unstemmed | Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery |
| title_short | Robot‐assisted thymectomy in large anterior mediastinal tumors: A comparative study with video‐assisted thymectomy and open surgery |
| title_sort | robot assisted thymectomy in large anterior mediastinal tumors a comparative study with video assisted thymectomy and open surgery |
| topic | anterior mediastinal tumor robot‐assisted thymectomy video‐assisted thymectomy |
| url | https://doi.org/10.1111/1759-7714.14744 |
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