Effect of noise in intelligent cellular decision making.

Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons,...

Full description

Bibliographic Details
Main Authors: Russell Bates, Oleg Blyuss, Ahmed Alsaedi, Alexey Zaikin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4429125?pdf=render
_version_ 1819065271759929344
author Russell Bates
Oleg Blyuss
Ahmed Alsaedi
Alexey Zaikin
author_facet Russell Bates
Oleg Blyuss
Ahmed Alsaedi
Alexey Zaikin
author_sort Russell Bates
collection DOAJ
description Similar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons, simple intelligent schemes known from studies on Artificial Intelligence. We study the role of genetic noise in intelligent decision making at the genetic level and show that noise can play a constructive role helping cells to make a proper decision. We show this using the example of a simple genetic classifier able to classify two external stimuli.
first_indexed 2024-12-21T15:43:49Z
format Article
id doaj.art-5643737d4ed649128c5bee35bfd2a1b9
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-12-21T15:43:49Z
publishDate 2015-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-5643737d4ed649128c5bee35bfd2a1b92022-12-21T18:58:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01105e012507910.1371/journal.pone.0125079Effect of noise in intelligent cellular decision making.Russell BatesOleg BlyussAhmed AlsaediAlexey ZaikinSimilar to intelligent multicellular neural networks controlling human brains, even single cells, surprisingly, are able to make intelligent decisions to classify several external stimuli or to associate them. This happens because of the fact that gene regulatory networks can perform as perceptrons, simple intelligent schemes known from studies on Artificial Intelligence. We study the role of genetic noise in intelligent decision making at the genetic level and show that noise can play a constructive role helping cells to make a proper decision. We show this using the example of a simple genetic classifier able to classify two external stimuli.http://europepmc.org/articles/PMC4429125?pdf=render
spellingShingle Russell Bates
Oleg Blyuss
Ahmed Alsaedi
Alexey Zaikin
Effect of noise in intelligent cellular decision making.
PLoS ONE
title Effect of noise in intelligent cellular decision making.
title_full Effect of noise in intelligent cellular decision making.
title_fullStr Effect of noise in intelligent cellular decision making.
title_full_unstemmed Effect of noise in intelligent cellular decision making.
title_short Effect of noise in intelligent cellular decision making.
title_sort effect of noise in intelligent cellular decision making
url http://europepmc.org/articles/PMC4429125?pdf=render
work_keys_str_mv AT russellbates effectofnoiseinintelligentcellulardecisionmaking
AT olegblyuss effectofnoiseinintelligentcellulardecisionmaking
AT ahmedalsaedi effectofnoiseinintelligentcellulardecisionmaking
AT alexeyzaikin effectofnoiseinintelligentcellulardecisionmaking