Pre-Pregnancy Adherence to Mediterranean Diet and Risk of Gestational Diabetes Mellitus: A Prospective Cohort Study in Greece

Gestational Diabetes Mellitus (GDM) is a growing epidemic affecting pregnant women and their offspring. This study aimed to identify the relationship between adherence to a Mediterranean diet (MD) before conception and the risk of GDM in a contemporary Greek pregnant cohort. A prospective cohort of...

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Bibliographic Details
Main Authors: Antigoni Tranidou, Themistoklis Dagklis, Emmanuella Magriplis, Aikaterini Apostolopoulou, Ioannis Tsakiridis, Violeta Chroni, Eirini Tsekitsidi, Ioustini Kalaitzopoulou, Nikolaos Pazaras, Michail Chourdakis
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nutrients
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Online Access:https://www.mdpi.com/2072-6643/15/4/848
Description
Summary:Gestational Diabetes Mellitus (GDM) is a growing epidemic affecting pregnant women and their offspring. This study aimed to identify the relationship between adherence to a Mediterranean diet (MD) before conception and the risk of GDM in a contemporary Greek pregnant cohort. A prospective cohort of pregnant women was recruited at the routine first trimester visit. Nutritional intake was evaluated using a population specific validated food frequency questionnaire (FFQ). Pre-pregnancy adherence to MD was derived using two different scoring systems, the Mediterranean diet index score (MDS), and a modified version. Adjusted odds ratios (aOR) were computed using multiple logistic regression models for each score derived. Of 743 participating women, 112 (15.1%) developed GDM. The MDS index showed that scoring 5–9 points (high adherence) was associated with a lower GDM incidence (aOR: 0.57 95% CI (0.32, 0.90), <i>p</i> = 0.02), while the modified MDS index showed no significant association for any level of adherence. Pre-pregnancy consumption of “meat and derivatives” and “fatty meat and processed meat” was associated with a higher risk of GDM, with both scoring systems (<i>p</i> = 0.008, <i>p</i> = 0.004, respectively). A higher adherence to a MD pre-pregnancy, especially with less meat consumption, may have a protective effect on the occurrence of GDM.
ISSN:2072-6643