Practices related to late‐onset sepsis in very low‐birth weight preterm infants

Objective: To understand the practices related to late‐onset sepsis (LOS) in the centers of the Brazilian Neonatal Research Network, and to propose strategies to reduce the incidence of LOS. Methods: This was a cross‐sectional descriptive multicenter study approved by the Ethics Committee. Three que...

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Main Authors: Maria Regina Bentlin, Ligia M.S.S. Rugolo, Ligia S.L. Ferrari
Format: Article
Language:Portuguese
Published: Brazilian Society of Pediatrics 2015-03-01
Series:Jornal de Pediatria (Versão em Português)
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2255553615000154
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author Maria Regina Bentlin
Ligia M.S.S. Rugolo
Ligia S.L. Ferrari
author_facet Maria Regina Bentlin
Ligia M.S.S. Rugolo
Ligia S.L. Ferrari
author_sort Maria Regina Bentlin
collection DOAJ
description Objective: To understand the practices related to late‐onset sepsis (LOS) in the centers of the Brazilian Neonatal Research Network, and to propose strategies to reduce the incidence of LOS. Methods: This was a cross‐sectional descriptive multicenter study approved by the Ethics Committee. Three questionnaires regarding hand hygiene, vascular catheters, and diagnosis/treatment of LOS were sent to the coordinator of each center. The center with the lowest incidence of LOS was compared with the others. Results: All 16 centers answered the questionnaires. Regarding hand hygiene, 87% use chlorhexidine or 70% alcohol; alcohol gel is used in 100%; 80% use bedside dispensers (50% had one dispenser for every two beds); practical training occurs in 100% and theoretical training in 70% of the centers, and 37% train once a year. Catheters: 94% have a protocol, and 75% have a line insertion team. Diagnosis/treatment: complete blood count and blood culture are used in 100%, PCR in 87%, hematological scores in 75%; oxacillin and aminoglycosides is the empirical therapy in 50% of centers. Characteristics of the center with lowest incidence of LOS: stricter hand hygiene; catheter insertion and maintenance groups; use of blood culture, PCR, and hematological score for diagnosis; empirical therapy with oxacillin and aminoglycoside. Conclusion: The knowledge of the practices of each center allowed for the identification of aspects to be improved as a strategy to reduce LOS, including: alcohol gel use, hand hygiene training, implementation of catheter teams, and wise use of antibiotic therapy.
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spelling doaj.art-564520c0e6e7446ba3be0a73c9dbd0e62022-12-22T03:23:32ZporBrazilian Society of PediatricsJornal de Pediatria (Versão em Português)2255-55362015-03-0191216817410.1016/j.jpedp.2014.07.004Practices related to late‐onset sepsis in very low‐birth weight preterm infantsMaria Regina Bentlin0Ligia M.S.S. Rugolo1Ligia S.L. Ferrari2Hospital das Clínicas, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp), Botucatu, SP, BrasilHospital das Clínicas, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp), Botucatu, SP, BrasilHospital Universitário de Londrina, Universidade Estadual de Londrina (UEL), Londrina, PR, BrasilObjective: To understand the practices related to late‐onset sepsis (LOS) in the centers of the Brazilian Neonatal Research Network, and to propose strategies to reduce the incidence of LOS. Methods: This was a cross‐sectional descriptive multicenter study approved by the Ethics Committee. Three questionnaires regarding hand hygiene, vascular catheters, and diagnosis/treatment of LOS were sent to the coordinator of each center. The center with the lowest incidence of LOS was compared with the others. Results: All 16 centers answered the questionnaires. Regarding hand hygiene, 87% use chlorhexidine or 70% alcohol; alcohol gel is used in 100%; 80% use bedside dispensers (50% had one dispenser for every two beds); practical training occurs in 100% and theoretical training in 70% of the centers, and 37% train once a year. Catheters: 94% have a protocol, and 75% have a line insertion team. Diagnosis/treatment: complete blood count and blood culture are used in 100%, PCR in 87%, hematological scores in 75%; oxacillin and aminoglycosides is the empirical therapy in 50% of centers. Characteristics of the center with lowest incidence of LOS: stricter hand hygiene; catheter insertion and maintenance groups; use of blood culture, PCR, and hematological score for diagnosis; empirical therapy with oxacillin and aminoglycoside. Conclusion: The knowledge of the practices of each center allowed for the identification of aspects to be improved as a strategy to reduce LOS, including: alcohol gel use, hand hygiene training, implementation of catheter teams, and wise use of antibiotic therapy.http://www.sciencedirect.com/science/article/pii/S2255553615000154SepsisNewbornPrematureHand hygienePrevention and control
spellingShingle Maria Regina Bentlin
Ligia M.S.S. Rugolo
Ligia S.L. Ferrari
Practices related to late‐onset sepsis in very low‐birth weight preterm infants
Jornal de Pediatria (Versão em Português)
Sepsis
Newborn
Premature
Hand hygiene
Prevention and control
title Practices related to late‐onset sepsis in very low‐birth weight preterm infants
title_full Practices related to late‐onset sepsis in very low‐birth weight preterm infants
title_fullStr Practices related to late‐onset sepsis in very low‐birth weight preterm infants
title_full_unstemmed Practices related to late‐onset sepsis in very low‐birth weight preterm infants
title_short Practices related to late‐onset sepsis in very low‐birth weight preterm infants
title_sort practices related to late onset sepsis in very low birth weight preterm infants
topic Sepsis
Newborn
Premature
Hand hygiene
Prevention and control
url http://www.sciencedirect.com/science/article/pii/S2255553615000154
work_keys_str_mv AT mariareginabentlin practicesrelatedtolateonsetsepsisinverylowbirthweightpreterminfants
AT ligiamssrugolo practicesrelatedtolateonsetsepsisinverylowbirthweightpreterminfants
AT ligiaslferrari practicesrelatedtolateonsetsepsisinverylowbirthweightpreterminfants