Cell foundry with high product specificity and catalytic activity for 21-deoxycortisol biotransformation
Abstract Background 21-deoxycortisol (21-DF) is the key intermediate to manufacture pharmaceutical glucocorticoids. Recently, a Japan patent has realized 21-DF production via biotransformation of 17-hydroxyprogesterone (17-OHP) by purified steroid 11β-hydroxylase CYP11B1. Due to the less costs on en...
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
BMC
2017-06-01
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| श्रृंखला: | Microbial Cell Factories |
| विषय: | |
| ऑनलाइन पहुंच: | http://link.springer.com/article/10.1186/s12934-017-0720-y |