Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer?
Many factors contribute to mortality in lung cancer, including the presence of concomitant cardiovascular disease. In the treatment of early stage of lung cancer, the presence of comorbidities and occurence of cardiotoxicity may be prognostic. The effect of cardiotoxicity of radiotherapy and chemora...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.984951/full |
| _version_ | 1811265804160729088 |
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| author | Sabina Mędrek Sebastian Szmit |
| author_facet | Sabina Mędrek Sebastian Szmit |
| author_sort | Sabina Mędrek |
| collection | DOAJ |
| description | Many factors contribute to mortality in lung cancer, including the presence of concomitant cardiovascular disease. In the treatment of early stage of lung cancer, the presence of comorbidities and occurence of cardiotoxicity may be prognostic. The effect of cardiotoxicity of radiotherapy and chemoradiotherapy on overall survival has been documented. Acute arterial and venous thromboembolic events seem to correlate with the degree of the histological malignancy, its clinical advancement, and even with optimal cardiac treatment, they may influence the survival time. In the case of high-grade and advanced lung cancer stage especially in an unresectable stadium, the prognosis depends primarily on the factors related to the histopathological and molecular diagnosis. Electrocardiographic and echocardiographic abnormalities may be prognostic factors, as they seem to correlate with the patient's performance status as well as tumor localization and size. |
| first_indexed | 2024-04-12T20:30:33Z |
| format | Article |
| id | doaj.art-564b1d9e6f964bddb6ae5cfe49b5da0a |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T20:30:33Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-564b1d9e6f964bddb6ae5cfe49b5da0a2022-12-22T03:17:46ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-09-01910.3389/fcvm.2022.984951984951Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer?Sabina Mędrek0Sebastian Szmit1Department of Cardiology, Subcarpathian Oncological Center, Brzozów, PolandDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education, European Health Centre, Otwock, PolandMany factors contribute to mortality in lung cancer, including the presence of concomitant cardiovascular disease. In the treatment of early stage of lung cancer, the presence of comorbidities and occurence of cardiotoxicity may be prognostic. The effect of cardiotoxicity of radiotherapy and chemoradiotherapy on overall survival has been documented. Acute arterial and venous thromboembolic events seem to correlate with the degree of the histological malignancy, its clinical advancement, and even with optimal cardiac treatment, they may influence the survival time. In the case of high-grade and advanced lung cancer stage especially in an unresectable stadium, the prognosis depends primarily on the factors related to the histopathological and molecular diagnosis. Electrocardiographic and echocardiographic abnormalities may be prognostic factors, as they seem to correlate with the patient's performance status as well as tumor localization and size.https://www.frontiersin.org/articles/10.3389/fcvm.2022.984951/fulllung cancercardio-oncologysurvivalprognosisheart failurethromboembolism |
| spellingShingle | Sabina Mędrek Sebastian Szmit Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? Frontiers in Cardiovascular Medicine lung cancer cardio-oncology survival prognosis heart failure thromboembolism |
| title | Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? |
| title_full | Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? |
| title_fullStr | Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? |
| title_full_unstemmed | Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? |
| title_short | Are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer? |
| title_sort | are cardiovascular comorbidities always associated with a worse prognosis in patients with lung cancer |
| topic | lung cancer cardio-oncology survival prognosis heart failure thromboembolism |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.984951/full |
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