Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry
The attractive structural and mechanical properties of cellulose substrates (paper, cloth, and thread), including passive fluid transport, biocompatibility, durability, and flexibility, have attracted researchers in the past few decades to explore them as alternative microfluidic platforms. The inco...
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| Format: | Article |
| Language: | English |
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De Gruyter
2017-07-01
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| Series: | Reviews in Analytical Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/revac-2016-0018 |
| _version_ | 1818734375600128000 |
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| author | Malon Radha S.P. Heng Lee Yook Córcoles Emma P. |
| author_facet | Malon Radha S.P. Heng Lee Yook Córcoles Emma P. |
| author_sort | Malon Radha S.P. |
| collection | DOAJ |
| description | The attractive structural and mechanical properties of cellulose substrates (paper, cloth, and thread), including passive fluid transport, biocompatibility, durability, and flexibility, have attracted researchers in the past few decades to explore them as alternative microfluidic platforms. The incorporation of electrochemical (EC) sensing broadened their use for applications such as clinical diagnosis, pharmaceutical chemical analyses, food quality, and environmental monitoring. This article provides a review on the microfluidic devices constructed on paper, cloth, and thread substrates. It begins with an overview on paper-based microfluidic devices, followed by an in-depth review on the various applications of EC detection incorporated on paper-based microfluidic devices reported to date. The review on paper-based microfluidic devices attempts to convey a few perspective directions that cloth- and thread-based microfluidic devices may take in its development. Finally, the research efforts on the development and evaluation, as well as current limitations of cloth- and thread-based microfluidic devices are discussed. Microfluidic devices constructed on paper, cloth, and thread substrates are still at an early development stage (prototype) requiring several improvements in terms of fabrication, analytical techniques, and performance to become mature platforms that can be adapted and commercialized as real world products. However, they hold a promising potential as wearable devices. |
| first_indexed | 2024-12-18T00:04:22Z |
| format | Article |
| id | doaj.art-565d0c3d51474b639a76f7042bca4da1 |
| institution | Directory Open Access Journal |
| issn | 0793-0135 2191-0189 |
| language | English |
| last_indexed | 2024-12-18T00:04:22Z |
| publishDate | 2017-07-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Reviews in Analytical Chemistry |
| spelling | doaj.art-565d0c3d51474b639a76f7042bca4da12022-12-21T21:27:50ZengDe GruyterReviews in Analytical Chemistry0793-01352191-01892017-07-013641811182410.1515/revac-2016-0018Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistryMalon Radha S.P.0Heng Lee Yook1Córcoles Emma P.2Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor Darul Ehsan, MalaysiaFaculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Selangor Darul Ehsan, MalaysiaInstituto de Microelectrónica de Barcelona, Centro Nacional de Microelectrónica (IMB-CNM, CSIC), Campus Universidad Autónoma de Barcelona, 08193 Bellaterra Barcelona, SpainThe attractive structural and mechanical properties of cellulose substrates (paper, cloth, and thread), including passive fluid transport, biocompatibility, durability, and flexibility, have attracted researchers in the past few decades to explore them as alternative microfluidic platforms. The incorporation of electrochemical (EC) sensing broadened their use for applications such as clinical diagnosis, pharmaceutical chemical analyses, food quality, and environmental monitoring. This article provides a review on the microfluidic devices constructed on paper, cloth, and thread substrates. It begins with an overview on paper-based microfluidic devices, followed by an in-depth review on the various applications of EC detection incorporated on paper-based microfluidic devices reported to date. The review on paper-based microfluidic devices attempts to convey a few perspective directions that cloth- and thread-based microfluidic devices may take in its development. Finally, the research efforts on the development and evaluation, as well as current limitations of cloth- and thread-based microfluidic devices are discussed. Microfluidic devices constructed on paper, cloth, and thread substrates are still at an early development stage (prototype) requiring several improvements in terms of fabrication, analytical techniques, and performance to become mature platforms that can be adapted and commercialized as real world products. However, they hold a promising potential as wearable devices.https://doi.org/10.1515/revac-2016-0018biosensorelectrochemicalmicrofluidicspaperfabric |
| spellingShingle | Malon Radha S.P. Heng Lee Yook Córcoles Emma P. Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry Reviews in Analytical Chemistry biosensor electrochemical microfluidics paper fabric |
| title | Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry |
| title_full | Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry |
| title_fullStr | Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry |
| title_full_unstemmed | Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry |
| title_short | Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry |
| title_sort | recent developments in microfluidic paper cloth and thread based electrochemical devices for analytical chemistry |
| topic | biosensor electrochemical microfluidics paper fabric |
| url | https://doi.org/10.1515/revac-2016-0018 |
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