<i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review
Mango and its by-products have traditional medicinal uses. They contain diverse bioactive compounds offering numerous health benefits, including cardioprotective and metabolic properties. This study aimed to explore the impact of mango fruit and its by-products on human health, emphasizing its metab...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/12/2270 |
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| author | Giulia Minniti Lucas Fornari Laurindo Nathalia Mendes Machado Lidiane Gonsalves Duarte Elen Landgraf Guiguer Adriano Cressoni Araujo Jefferson Aparecido Dias Caroline Barbalho Lamas Yandra Crevelin Nunes Marcelo Dib Bechara Edgar Baldi Júnior Fabrício Bertoli Gimenes Sandra Maria Barbalho |
| author_facet | Giulia Minniti Lucas Fornari Laurindo Nathalia Mendes Machado Lidiane Gonsalves Duarte Elen Landgraf Guiguer Adriano Cressoni Araujo Jefferson Aparecido Dias Caroline Barbalho Lamas Yandra Crevelin Nunes Marcelo Dib Bechara Edgar Baldi Júnior Fabrício Bertoli Gimenes Sandra Maria Barbalho |
| author_sort | Giulia Minniti |
| collection | DOAJ |
| description | Mango and its by-products have traditional medicinal uses. They contain diverse bioactive compounds offering numerous health benefits, including cardioprotective and metabolic properties. This study aimed to explore the impact of mango fruit and its by-products on human health, emphasizing its metabolic syndrome components. PUBMED, EMBASE, COCHRANE, and GOOGLE SCHOLAR were searched following PRISMA guidelines, and the COCHRANE handbook was utilized to assess bias risks. In vivo and in vitro studies have shown several benefits of mango and its by-products. For this systematic review, 13 studies met the inclusion criteria. The collective findings indicated that the utilization of mango in various forms—ranging from fresh mango slices and mango puree to mango by-products, mango leaf extract, fruit powder, and mangiferin—yielded many favorable effects. These encompassed enhancements in glycemic control and improvements in plasma lipid profiles. Additionally, mango reduces food intake, elevates mood scores, augments physical performance during exercise, improves endothelial function, and decreases the incidence of respiratory tract infections. Utilizing mango by-products supports the demand for healthier products. This approach also aids in environmental conservation. Furthermore, the development of mango-derived nanomedicines aligns with sustainable goals and offers innovative solutions for healthcare challenges whilst being environmentally conscious. |
| first_indexed | 2024-03-08T20:35:45Z |
| format | Article |
| id | doaj.art-566141b6b83043548888282a2c5e1c05 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-08T20:35:45Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-566141b6b83043548888282a2c5e1c052023-12-22T14:21:08ZengMDPI AGLife2075-17292023-11-011312227010.3390/life13122270<i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic ReviewGiulia Minniti0Lucas Fornari Laurindo1Nathalia Mendes Machado2Lidiane Gonsalves Duarte3Elen Landgraf Guiguer4Adriano Cressoni Araujo5Jefferson Aparecido Dias6Caroline Barbalho Lamas7Yandra Crevelin Nunes8Marcelo Dib Bechara9Edgar Baldi Júnior10Fabrício Bertoli Gimenes11Sandra Maria Barbalho12Department of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília 17500-000, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília 17500-000, SP, BrazilDepartment of Gerontology, School of Gerontology, Universidade Federal de São Carlos (UFSCar), São Carlos 13565-905, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Faculdade de Medicina de Marília (FAMEMA), Marília 17519-030, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília 17500-000, SP, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Marília 17500-000, SP, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, Universidade de Marília (UNIMAR), Marília 17525-902, SP, BrazilMango and its by-products have traditional medicinal uses. They contain diverse bioactive compounds offering numerous health benefits, including cardioprotective and metabolic properties. This study aimed to explore the impact of mango fruit and its by-products on human health, emphasizing its metabolic syndrome components. PUBMED, EMBASE, COCHRANE, and GOOGLE SCHOLAR were searched following PRISMA guidelines, and the COCHRANE handbook was utilized to assess bias risks. In vivo and in vitro studies have shown several benefits of mango and its by-products. For this systematic review, 13 studies met the inclusion criteria. The collective findings indicated that the utilization of mango in various forms—ranging from fresh mango slices and mango puree to mango by-products, mango leaf extract, fruit powder, and mangiferin—yielded many favorable effects. These encompassed enhancements in glycemic control and improvements in plasma lipid profiles. Additionally, mango reduces food intake, elevates mood scores, augments physical performance during exercise, improves endothelial function, and decreases the incidence of respiratory tract infections. Utilizing mango by-products supports the demand for healthier products. This approach also aids in environmental conservation. Furthermore, the development of mango-derived nanomedicines aligns with sustainable goals and offers innovative solutions for healthcare challenges whilst being environmentally conscious.https://www.mdpi.com/2075-1729/13/12/2270<i>Mangifera indica</i> L.by-productsantioxidantanti-inflammatorydiabetesobesity |
| spellingShingle | Giulia Minniti Lucas Fornari Laurindo Nathalia Mendes Machado Lidiane Gonsalves Duarte Elen Landgraf Guiguer Adriano Cressoni Araujo Jefferson Aparecido Dias Caroline Barbalho Lamas Yandra Crevelin Nunes Marcelo Dib Bechara Edgar Baldi Júnior Fabrício Bertoli Gimenes Sandra Maria Barbalho <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review Life <i>Mangifera indica</i> L. by-products antioxidant anti-inflammatory diabetes obesity |
| title | <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review |
| title_full | <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review |
| title_fullStr | <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review |
| title_full_unstemmed | <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review |
| title_short | <i>Mangifera indica</i> L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review |
| title_sort | i mangifera indica i l by products and mangiferin on cardio metabolic and other health conditions a systematic review |
| topic | <i>Mangifera indica</i> L. by-products antioxidant anti-inflammatory diabetes obesity |
| url | https://www.mdpi.com/2075-1729/13/12/2270 |
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