Blood flow effects in a patient with a thoracic aortic endovascular prosthesis
This work analyzes hemodynamic phenomena within the aorta of two elderly patients and their impact on blood flow behavior, particularly affected by an endovascular prosthesis in one of them (Patient II). Computational Fluid Dynamics (CFD) was utilized for this study, involving measurements of veloci...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024023867 |
| _version_ | 1797259856017620992 |
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| author | Juan P. Tello Juan C. Velez Alberto Cadena Andres Jutinico Mauricio Pardo Winston Percybrooks |
| author_facet | Juan P. Tello Juan C. Velez Alberto Cadena Andres Jutinico Mauricio Pardo Winston Percybrooks |
| author_sort | Juan P. Tello |
| collection | DOAJ |
| description | This work analyzes hemodynamic phenomena within the aorta of two elderly patients and their impact on blood flow behavior, particularly affected by an endovascular prosthesis in one of them (Patient II). Computational Fluid Dynamics (CFD) was utilized for this study, involving measurements of velocity, pressure, and wall shear stress (WSS) at various time points during the third cardiac cycle, at specific positions within two cross sections of the thoracic aorta. The first cross-section (Cross-Section 1, CS1) is located before the initial fluid bifurcation, just before the right subclavian artery. The second cross-section (Cross-Section 2, CS2) is situated immediately after the left subclavian artery. The results reveal that, under regular aortic geometries, velocity and pressure magnitudes follow the principles of fluid dynamics, displaying variations. However, in Patient II, an endoprosthesis near the CS2 and the proximal border of the endoprosthesis significantly disrupts fluid behavior owing to the pulsatile flow. The cross-sectional areas of Patient I are smaller than those of Patient II, leading to higher flow magnitudes. Although in CS1 of Patient I, there is considerable variability in velocity magnitudes, they exhibit a more uniform and predictable transition. In contrast, CS2 of Patient II, where magnitude variation is also high, displays irregular fluid behavior due to the endoprosthesis presence. This cross-section coincides with the border of the fluid bifurcation. Additionally, the irregular geometry caused by endovascular aneurysm repair contributes to flow disruption as the endoprosthesis adjusts to the endothelium, reshaping itself to conform with the vessel wall. In this context, significant alterations in velocity values, pressure differentials fluctuating by up to 10%, and low wall shear stress indicate the pronounced influence of the endovascular prosthesis on blood flow behavior. These flow disturbances, when compounded by the heart rate, can potentially lead to changes in vascular anatomy and displacement, resulting in a disruption of the prosthesis-endothelium continuity and thereby causing clinical complications in the patient. |
| first_indexed | 2024-03-07T20:04:01Z |
| format | Article |
| id | doaj.art-566146d9a7ba4934bc61353fd7ee2ae7 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T23:16:04Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-566146d9a7ba4934bc61353fd7ee2ae72024-03-17T07:55:19ZengElsevierHeliyon2405-84402024-03-01105e26355Blood flow effects in a patient with a thoracic aortic endovascular prosthesisJuan P. Tello0Juan C. Velez1Alberto Cadena2Andres Jutinico3Mauricio Pardo4Winston Percybrooks5Universidad del Norte, Km. 5 Via Puerto Colombia, Barranquilla, Colombia; Corresponding author.Universidad del Norte, Km. 5 Via Puerto Colombia, Barranquilla, ColombiaClinica de la Costa, Barranquilla, ColombiaUniversidad Distrital Francisco Jose de Caldas, Bogota, ColombiaUniversidad del Norte, Km. 5 Via Puerto Colombia, Barranquilla, ColombiaUniversidad del Norte, Km. 5 Via Puerto Colombia, Barranquilla, ColombiaThis work analyzes hemodynamic phenomena within the aorta of two elderly patients and their impact on blood flow behavior, particularly affected by an endovascular prosthesis in one of them (Patient II). Computational Fluid Dynamics (CFD) was utilized for this study, involving measurements of velocity, pressure, and wall shear stress (WSS) at various time points during the third cardiac cycle, at specific positions within two cross sections of the thoracic aorta. The first cross-section (Cross-Section 1, CS1) is located before the initial fluid bifurcation, just before the right subclavian artery. The second cross-section (Cross-Section 2, CS2) is situated immediately after the left subclavian artery. The results reveal that, under regular aortic geometries, velocity and pressure magnitudes follow the principles of fluid dynamics, displaying variations. However, in Patient II, an endoprosthesis near the CS2 and the proximal border of the endoprosthesis significantly disrupts fluid behavior owing to the pulsatile flow. The cross-sectional areas of Patient I are smaller than those of Patient II, leading to higher flow magnitudes. Although in CS1 of Patient I, there is considerable variability in velocity magnitudes, they exhibit a more uniform and predictable transition. In contrast, CS2 of Patient II, where magnitude variation is also high, displays irregular fluid behavior due to the endoprosthesis presence. This cross-section coincides with the border of the fluid bifurcation. Additionally, the irregular geometry caused by endovascular aneurysm repair contributes to flow disruption as the endoprosthesis adjusts to the endothelium, reshaping itself to conform with the vessel wall. In this context, significant alterations in velocity values, pressure differentials fluctuating by up to 10%, and low wall shear stress indicate the pronounced influence of the endovascular prosthesis on blood flow behavior. These flow disturbances, when compounded by the heart rate, can potentially lead to changes in vascular anatomy and displacement, resulting in a disruption of the prosthesis-endothelium continuity and thereby causing clinical complications in the patient.http://www.sciencedirect.com/science/article/pii/S2405844024023867Blood flowVelocity profilesPressure distributionsImage processingAortaCross section |
| spellingShingle | Juan P. Tello Juan C. Velez Alberto Cadena Andres Jutinico Mauricio Pardo Winston Percybrooks Blood flow effects in a patient with a thoracic aortic endovascular prosthesis Heliyon Blood flow Velocity profiles Pressure distributions Image processing Aorta Cross section |
| title | Blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| title_full | Blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| title_fullStr | Blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| title_full_unstemmed | Blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| title_short | Blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| title_sort | blood flow effects in a patient with a thoracic aortic endovascular prosthesis |
| topic | Blood flow Velocity profiles Pressure distributions Image processing Aorta Cross section |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024023867 |
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