Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report
We present a case of life-threatening pneumonia caused by Pseudomonas aeruginosa (P. aeruginosa) in a healthy 67-year-old man. Rapid disseminated infection resulted in the right hemorrhagic pneumonia and bacteremia. Antimicrobial therapy had limited effects, radical pneumonectomy eventually resolved...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007122000958 |
| _version_ | 1828367714921480192 |
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| author | Yasumaro Fujiki Naoko Mato Shinya Watanabe Tomoki Shibano Ken Tonai Kento Takahashi Tatsuya Saito Akiko Okuyama Ayako Takigami Masashi Bando Takuji Suzuki Longzhu Cui Koichi Hagiwara |
| author_facet | Yasumaro Fujiki Naoko Mato Shinya Watanabe Tomoki Shibano Ken Tonai Kento Takahashi Tatsuya Saito Akiko Okuyama Ayako Takigami Masashi Bando Takuji Suzuki Longzhu Cui Koichi Hagiwara |
| author_sort | Yasumaro Fujiki |
| collection | DOAJ |
| description | We present a case of life-threatening pneumonia caused by Pseudomonas aeruginosa (P. aeruginosa) in a healthy 67-year-old man. Rapid disseminated infection resulted in the right hemorrhagic pneumonia and bacteremia. Antimicrobial therapy had limited effects, radical pneumonectomy eventually resolved the prolonged infection. Concurrently, we explored the environmental factors responsible for fulminant P. aeruginosa infection. Multi-locus sequence typing demonstrated that P. aeruginosa isolated from the patient was identical to that collected from home whirlpool bath by the common virulent factor gene. Massive inhalation of contaminated aerosol and pathogen virulence may have synergistically contributed to the severity in this case. |
| first_indexed | 2024-04-14T06:01:39Z |
| format | Article |
| id | doaj.art-5662b4bf78214713b10e49080cdaa32c |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-04-14T06:01:39Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-5662b4bf78214713b10e49080cdaa32c2022-12-22T02:08:43ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0138101673Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case reportYasumaro Fujiki0Naoko Mato1Shinya Watanabe2Tomoki Shibano3Ken Tonai4Kento Takahashi5Tatsuya Saito6Akiko Okuyama7Ayako Takigami8Masashi Bando9Takuji Suzuki10Longzhu Cui11Koichi Hagiwara12Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan; Corresponding author. 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.Division of Bacteriology, School of Medicine, Jichi Medical University, Tochigi, JapanDivision of General Thoracic Surgery, Department of Surgery, Jichi Medical University, Tochigi, JapanDivision of Intensive Care, Department of Anesthesiology & Intensive Care Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanDepartment of Respirology, Graduate School of Medicine, Chiba University, Chiba, JapanDivision of Bacteriology, School of Medicine, Jichi Medical University, Tochigi, JapanDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, JapanWe present a case of life-threatening pneumonia caused by Pseudomonas aeruginosa (P. aeruginosa) in a healthy 67-year-old man. Rapid disseminated infection resulted in the right hemorrhagic pneumonia and bacteremia. Antimicrobial therapy had limited effects, radical pneumonectomy eventually resolved the prolonged infection. Concurrently, we explored the environmental factors responsible for fulminant P. aeruginosa infection. Multi-locus sequence typing demonstrated that P. aeruginosa isolated from the patient was identical to that collected from home whirlpool bath by the common virulent factor gene. Massive inhalation of contaminated aerosol and pathogen virulence may have synergistically contributed to the severity in this case.http://www.sciencedirect.com/science/article/pii/S2213007122000958Pseudomonas aeruginosa (P. aeruginosa)Whirlpool bathMulti-locus sequence typing (MLST)Exoenzyme S (exoS) geneExo S |
| spellingShingle | Yasumaro Fujiki Naoko Mato Shinya Watanabe Tomoki Shibano Ken Tonai Kento Takahashi Tatsuya Saito Akiko Okuyama Ayako Takigami Masashi Bando Takuji Suzuki Longzhu Cui Koichi Hagiwara Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report Respiratory Medicine Case Reports Pseudomonas aeruginosa (P. aeruginosa) Whirlpool bath Multi-locus sequence typing (MLST) Exoenzyme S (exoS) gene Exo S |
| title | Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report |
| title_full | Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report |
| title_fullStr | Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report |
| title_full_unstemmed | Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report |
| title_short | Virulent Pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath: A case report |
| title_sort | virulent pseudomonas aeruginosa pneumonia in an immunocompetent adult associated with a home whirlpool bath a case report |
| topic | Pseudomonas aeruginosa (P. aeruginosa) Whirlpool bath Multi-locus sequence typing (MLST) Exoenzyme S (exoS) gene Exo S |
| url | http://www.sciencedirect.com/science/article/pii/S2213007122000958 |
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