Long-Term Outcomes of Pediatric Renovascular Hypertension
Background/Aims: Renovascular hypertension (RVHT) is an important cause of childhood hypertension. This study evaluated the clinical characteristics and outcomes of Korean children with RVHT. Methods: Children treated for RVHT between 2000 and 2015 at our center were retrospectively reviewed. Result...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2017-09-01
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| Series: | Kidney & Blood Pressure Research |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/481549 |
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| author | Hyun Chung Jae Hwan Lee Eujin Park Hyesun Hyun Yo Han Ahn Hwan Jun Jae Gi Beom Kim Il Soo Ha Hae Il Cheong Hee Gyung Kang |
| author_facet | Hyun Chung Jae Hwan Lee Eujin Park Hyesun Hyun Yo Han Ahn Hwan Jun Jae Gi Beom Kim Il Soo Ha Hae Il Cheong Hee Gyung Kang |
| author_sort | Hyun Chung |
| collection | DOAJ |
| description | Background/Aims: Renovascular hypertension (RVHT) is an important cause of childhood hypertension. This study evaluated the clinical characteristics and outcomes of Korean children with RVHT. Methods: Children treated for RVHT between 2000 and 2015 at our center were retrospectively reviewed. Results: Forty-six children were followed for a median of 6.5 (0.66-27.23) years. Forty-five percutaneous transluminal angioplasties (PTAs) were performed in 32 children. At the last visit, clinical benefit was observed in 53.3% of children. Patients with comorbid cerebrovascular disease (CVD) showed less favorable long-term outcomes after PTA (clinical benefit in 41.7% vs. 61.1% in others) and higher restenosis rates (50% vs. 31.6% in others). Surgical procedures (bypass or nephrectomy) were performed in 8 patients. After surgery, blood pressure was normalized in 2 patients, improved in 3 patients, and unchanged in the remaining patients. Between PTA group (n=21) and medication group (n=14), percentage of atrophic kidneys became higher after follow-up period in medication group than in PTA group (60.0% vs. 26.1%, P=0.037). Conclusion: Aggressive treatment of pediatric RVHT yielded fair outcomes in our cohort. CVD comorbidity was associated with relatively poor PTA outcomes. To confirm our findings, larger cohort studies with a longer follow-up period are warranted. |
| first_indexed | 2024-04-12T08:20:54Z |
| format | Article |
| id | doaj.art-5663df331b8f4a758b7c8c57fb0e6b75 |
| institution | Directory Open Access Journal |
| issn | 1420-4096 1423-0143 |
| language | English |
| last_indexed | 2024-04-12T08:20:54Z |
| publishDate | 2017-09-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Kidney & Blood Pressure Research |
| spelling | doaj.art-5663df331b8f4a758b7c8c57fb0e6b752022-12-22T03:40:35ZengKarger PublishersKidney & Blood Pressure Research1420-40961423-01432017-09-0142361762710.1159/000481549481549Long-Term Outcomes of Pediatric Renovascular HypertensionHyun ChungJae Hwan LeeEujin ParkHyesun HyunYo Han AhnHwan Jun JaeGi Beom KimIl Soo HaHae Il CheongHee Gyung KangBackground/Aims: Renovascular hypertension (RVHT) is an important cause of childhood hypertension. This study evaluated the clinical characteristics and outcomes of Korean children with RVHT. Methods: Children treated for RVHT between 2000 and 2015 at our center were retrospectively reviewed. Results: Forty-six children were followed for a median of 6.5 (0.66-27.23) years. Forty-five percutaneous transluminal angioplasties (PTAs) were performed in 32 children. At the last visit, clinical benefit was observed in 53.3% of children. Patients with comorbid cerebrovascular disease (CVD) showed less favorable long-term outcomes after PTA (clinical benefit in 41.7% vs. 61.1% in others) and higher restenosis rates (50% vs. 31.6% in others). Surgical procedures (bypass or nephrectomy) were performed in 8 patients. After surgery, blood pressure was normalized in 2 patients, improved in 3 patients, and unchanged in the remaining patients. Between PTA group (n=21) and medication group (n=14), percentage of atrophic kidneys became higher after follow-up period in medication group than in PTA group (60.0% vs. 26.1%, P=0.037). Conclusion: Aggressive treatment of pediatric RVHT yielded fair outcomes in our cohort. CVD comorbidity was associated with relatively poor PTA outcomes. To confirm our findings, larger cohort studies with a longer follow-up period are warranted.http://www.karger.com/Article/FullText/481549Renovascular hypertensionPediatricsTreatmentAngioplastyLong-term outcome |
| spellingShingle | Hyun Chung Jae Hwan Lee Eujin Park Hyesun Hyun Yo Han Ahn Hwan Jun Jae Gi Beom Kim Il Soo Ha Hae Il Cheong Hee Gyung Kang Long-Term Outcomes of Pediatric Renovascular Hypertension Kidney & Blood Pressure Research Renovascular hypertension Pediatrics Treatment Angioplasty Long-term outcome |
| title | Long-Term Outcomes of Pediatric Renovascular Hypertension |
| title_full | Long-Term Outcomes of Pediatric Renovascular Hypertension |
| title_fullStr | Long-Term Outcomes of Pediatric Renovascular Hypertension |
| title_full_unstemmed | Long-Term Outcomes of Pediatric Renovascular Hypertension |
| title_short | Long-Term Outcomes of Pediatric Renovascular Hypertension |
| title_sort | long term outcomes of pediatric renovascular hypertension |
| topic | Renovascular hypertension Pediatrics Treatment Angioplasty Long-term outcome |
| url | http://www.karger.com/Article/FullText/481549 |
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