Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study.

Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study.

Previous studies of the HIV-1 disease have shown that HLA and Chemokine receptor genetic variants influence disease progression and early viral load. We performed a Genome Wide Association study in a cohort of 605 HIV-1-infected seroconverters for detection of novel genetic factors that influence pl...

Full description

Bibliographic Details
Main Authors:	Cyril Dalmasso, Wassila Carpentier, Laurence Meyer, Christine Rouzioux, Cécile Goujard, Marie-Laure Chaix, Olivier Lambotte, Véronique Avettand-Fenoel, Sigrid Le Clerc, Laure Denis de Senneville, Christiane Deveau, Faroudy Boufassa, Patrice Debré, Jean-François Delfraissy, Philippe Broet, Ioannis Theodorou, ANRS Genome Wide Association 01
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2008-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2603319?pdf=render

Similar Items

CD4 dynamics over a 15 year-period among HIV controllers enrolled in the ANRS French observatory.
by: Faroudy Boufassa, et al.
Published: (2011-01-01)

Immunologic and Virologic Progression in HIV Controllers: The Role of Viral "Blips" and Immune Activation in the ANRS CO21 CODEX Study.
by: Nicolas Noel, et al.
Published: (2015-01-01)

Early diagnosis of HIV-1 infection in newborns, in the context of prevention of mother-to-child transmission with HAART (Perinatal Cohort ANRS Co 01)
by: Warszawski Josiane, et al.
Published: (2008-04-01)

Total HIV DNA: a global marker of HIV persistence
by: Christine Rouzioux, et al.
Published: (2018-04-01)

Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study.
by: Asier Sáez-Cirión, et al.
Published: (2013-03-01)

New and old complex recombinant HIV-1 strains among patients with primary infection in 1996–2006 in France: The French ANRS CO06 primo cohort study
by: Peeters Martine, et al.
Published: (2008-08-01)

Detectable HIV-RNA in semen of HIV controllers.
by: Marie-Laure Chaix, et al.
Published: (2017-01-01)

Increasing contribution of integrated forms to total HIV DNA in blood during HIV disease progression from primary infectionResearch in context
by: Pauline Trémeaux, et al.
Published: (2019-03-01)

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control
by: Pauline Trémeaux, et al.
Published: (2023-02-01)

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
by: Angeline Rouers, et al.
Published: (2017-07-01)

Associations between 25-hydroxyvitamin D and immunologic, metabolic, inflammatory markers in treatment-naive HIV-infected persons: the ANRS CO9 «COPANA» cohort study.
by: Camille Legeai, et al.
Published: (2013-01-01)

X4 tropic multi-drug resistant quasi-species detected at the time of primary HIV-1 infection remain exclusive or at least dominant far from PHI.
by: Jade Ghosn, et al.
Published: (2011-01-01)

P16-45. High avidity CD4+ T cell response directed to an immunodominant Gag epitope in HIV controllers: an ANRS EP36 study
by: Thèze J, et al.
Published: (2009-10-01)

Recent HIV-1 infection contributes to the viral diffusion over the French territory with a recent increasing frequency.
by: Pierre Frange, et al.
Published: (2012-01-01)

Is clinical practice concordant with the changes in guidelines for antiretroviral therapy initiation during primary and chronic HIV-1 infection? The ANRS PRIMO and COPANA cohorts.
by: Evguenia Krastinova, et al.
Published: (2013-01-01)

What is the effect of self-identified HIV activism in willingness to participate in HIV cure-related clinical trials? Results from the ANRS-APSEC study
by: Marion Fiorentino, et al.
Published: (2019-07-01)

Gag-Specific CD4 and CD8 T-Cell Proliferation in Adolescents and Young Adults with Perinatally Acquired HIV-1 Infection Is Associated with Ethnicity - The ANRS-EP38-IMMIP Study.
by: Jérôme Le Chenadec, et al.
Published: (2015-01-01)

51 HIV patients and caregivers viewpoints towards participation to future HIV cure-related clinical trials – results from the second part of the French ANRS-APSEC survey
by: C. Protière, et al.
Published: (2016-07-01)

HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.
by: Benoît Vingert, et al.
Published: (2010-02-01)

Impact of early cART on HIV blood and semen compartments at the time of primary infection.
by: Antoine Chéret, et al.
Published: (2017-01-01)

Sexual behaviour and STIs among MSM living with HIV in the PrEP era: the French ANRS PRIMO cohort study
by: Virginie Baltes, et al.
Published: (2024-03-01)

HCV cure: an appropriate moment to reduce cannabis use in people living with HIV? (ANRS CO13 HEPAVIH data)
by: Tangui Barré, et al.
Published: (2022-03-01)

HIV-DNA in the genital tract of women on long-term effective therapy is associated to residual viremia and previous AIDS-defining illnesses.
by: Thierry Prazuck, et al.
Published: (2013-01-01)

Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers.
by: Stéphane Hua, et al.
Published: (2014-01-01)

Long-term spontaneous control of HIV-1 relates to low frequency of infected cells and inefficient viral reactivation
by: J.G. Prado, et al.
Published: (2015-12-01)

Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration.
by: Faroudy Boufassa, et al.
Published: (2014-01-01)

Impact of Early Versus Late Antiretroviral Treatment Initiation on Naive T Lymphocytes in HIV-1-Infected Children and Adolescents – The-ANRS-EP59-CLEAC Study
by: Pierre Frange, et al.
Published: (2021-04-01)

Coffee Intake and Neurocognitive Performance in HIV/HCV Coinfected Patients (ANRS CO13 HEPAVIH)
by: Saskia Antwerpes, et al.
Published: (2020-08-01)

Factors associated with unquantifiable total HIV-1 DNA in peripheral blood in persons living with HIV: An observational study
by: Aurélie Ram, et al.
Published: (2024-03-01)

Cellular immune responses induced with dose-sparing intradermal administration of HIV vaccine to HIV-uninfected volunteers in the ANRS VAC16 trial.
by: Odile Launay, et al.
Published: (2007-08-01)

Persistence of monocyte activation under treatment in people followed since acute HIV-1 infection relative to participants at high or low risk of HIV infection
by: Sophie Novelli, et al.
Published: (2020-12-01)

Machine Learning to Improve the Effectiveness of ANRS in Predicting HIV Drug Resistance
by: Yashik Singh
Published: (2017-10-01)

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control
by: Federico Perdomo-Celis, et al.
Published: (2023-01-01)

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control
by: Federico Perdomo-Celis, et al.
Published: (2022-06-01)

Increased liver stiffness is associated with mortality in HIV/HCV coinfected subjects: The French nationwide ANRS CO13 HEPAVIH cohort study.
by: Sarah Shili-Masmoudi, et al.
Published: (2019-01-01)

Tolerance and viral resistance after single-dose nevirapine (NVP) and short-course of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) to prevent mother-to-child transmission (PMTCT) of HIV-1: the TEmAA ANRS 12109 phase II trial, step 1
by: Ekouévi Didier, et al.
Published: (2008-04-01)

Correlation between HIV-2 RNA and HIV-2 total DNA levels
by: C. Charpentier, et al.
Published: (2015-12-01)

Patterns of patient and healthcare provider viewpoints regarding participation in HIV cure-related clinical trials. Findings from a multicentre French survey using Q methodology (ANRS-APSEC).
by: Christel Protière, et al.
Published: (2017-01-01)

A single HIV-1 cluster and a skewed immune homeostasis drive the early spread of HIV among resting CD4+ cell subsets within one month post-infection.
by: Charline Bacchus, et al.
Published: (2013-01-01)

The HIV RNA setpoint theory revisited
by: Hubert Jean-Baptiste, et al.
Published: (2007-09-01)