ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
ABSTRACT OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate a...
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Format: | Article |
Language: | English |
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University of Faisalabad
2015-09-01
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Series: | Journal of University Medical & Dental College |
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Online Access: | http://jumdc.com/index.php/jumdc/article/view/239 |
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author | Jamshid Ayatollahi Seyed Hossein Shahcheraghi et al. |
author_facet | Jamshid Ayatollahi Seyed Hossein Shahcheraghi et al. |
author_sort | Jamshid Ayatollahi |
collection | DOAJ |
description | ABSTRACT
OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate antimicrobial-resistance to Escherichia coli isolated from patients in Shahid Sadoughi hospital of Yazd.
METHODS: Antimicrobial susceptibility to cefixime, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimaxazole and nalidixic acid was determined for 492 E. coli isolates obtained from patients in Shahid Sadoughi hospital of Yazd in 2012.
RESULTS: In this study, imipenem was the most active agent (70.1% susceptible), followed by gentamicin and ciprofloxacin. High rates of resistance were observed to nalidixic acid (69.9%) and cotrimoxazole (62.2%).
CONCLUSIONS: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents and attempt to limit its spread |
first_indexed | 2024-04-12T14:47:10Z |
format | Article |
id | doaj.art-5667195d40874d33bf0c7813d4c79d5c |
institution | Directory Open Access Journal |
issn | 2221-7827 2310-5542 |
language | English |
last_indexed | 2024-04-12T14:47:10Z |
publishDate | 2015-09-01 |
publisher | University of Faisalabad |
record_format | Article |
series | Journal of University Medical & Dental College |
spelling | doaj.art-5667195d40874d33bf0c7813d4c79d5c2022-12-22T03:28:36ZengUniversity of FaisalabadJournal of University Medical & Dental College2221-78272310-55422015-09-0163ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRANJamshid Ayatollahi 0Seyed Hossein Shahcheraghi et al.1Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranSeyed Hossein Shahcheraghi, Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranABSTRACT OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate antimicrobial-resistance to Escherichia coli isolated from patients in Shahid Sadoughi hospital of Yazd. METHODS: Antimicrobial susceptibility to cefixime, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimaxazole and nalidixic acid was determined for 492 E. coli isolates obtained from patients in Shahid Sadoughi hospital of Yazd in 2012. RESULTS: In this study, imipenem was the most active agent (70.1% susceptible), followed by gentamicin and ciprofloxacin. High rates of resistance were observed to nalidixic acid (69.9%) and cotrimoxazole (62.2%). CONCLUSIONS: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents and attempt to limit its spreadhttp://jumdc.com/index.php/jumdc/article/view/239Escherichia coli- Antimicrobial agents- Resistance |
spellingShingle | Jamshid Ayatollahi Seyed Hossein Shahcheraghi et al. ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN Journal of University Medical & Dental College Escherichia coli- Antimicrobial agents- Resistance |
title | ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN |
title_full | ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN |
title_fullStr | ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN |
title_full_unstemmed | ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN |
title_short | ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN |
title_sort | antibiotic resistance of escherichia coli isolated from patients in shahid sadoughi hospital yazd iran |
topic | Escherichia coli- Antimicrobial agents- Resistance |
url | http://jumdc.com/index.php/jumdc/article/view/239 |
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