ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN

ABSTRACT OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate a...

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Main Authors: Jamshid Ayatollahi, Seyed Hossein Shahcheraghi et al.
Format: Article
Language:English
Published: University of Faisalabad 2015-09-01
Series:Journal of University Medical & Dental College
Subjects:
Online Access:http://jumdc.com/index.php/jumdc/article/view/239
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author Jamshid Ayatollahi
Seyed Hossein Shahcheraghi et al.
author_facet Jamshid Ayatollahi
Seyed Hossein Shahcheraghi et al.
author_sort Jamshid Ayatollahi
collection DOAJ
description ABSTRACT OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate antimicrobial-resistance to Escherichia coli isolated from patients in Shahid Sadoughi hospital of Yazd. METHODS: Antimicrobial susceptibility to cefixime, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimaxazole and nalidixic acid was determined for 492 E. coli isolates obtained from patients in Shahid Sadoughi hospital of Yazd in 2012. RESULTS: In this study, imipenem was the most active agent (70.1% susceptible), followed by gentamicin and ciprofloxacin. High rates of resistance were observed to nalidixic acid (69.9%) and cotrimoxazole (62.2%). CONCLUSIONS: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents and attempt to limit its spread
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spelling doaj.art-5667195d40874d33bf0c7813d4c79d5c2022-12-22T03:28:36ZengUniversity of FaisalabadJournal of University Medical & Dental College2221-78272310-55422015-09-0163ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRANJamshid Ayatollahi 0Seyed Hossein Shahcheraghi et al.1Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranSeyed Hossein Shahcheraghi, Infectious and Tropical Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IranABSTRACT OBJECTIVES: The enhancement of antibiotic resistance has been ascribed to a collection of microbial characteristics, the selective pressure of antibiotic use and social and technical vicissitudes that enhance the transmission of resistant organisms.The aim of this study was to investigate antimicrobial-resistance to Escherichia coli isolated from patients in Shahid Sadoughi hospital of Yazd. METHODS: Antimicrobial susceptibility to cefixime, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, cotrimaxazole and nalidixic acid was determined for 492 E. coli isolates obtained from patients in Shahid Sadoughi hospital of Yazd in 2012. RESULTS: In this study, imipenem was the most active agent (70.1% susceptible), followed by gentamicin and ciprofloxacin. High rates of resistance were observed to nalidixic acid (69.9%) and cotrimoxazole (62.2%). CONCLUSIONS: The investigation of antimicrobial susceptibility is essential, and will help to identify E. coli resistance to antimicrobial agents and attempt to limit its spreadhttp://jumdc.com/index.php/jumdc/article/view/239Escherichia coli- Antimicrobial agents- Resistance
spellingShingle Jamshid Ayatollahi
Seyed Hossein Shahcheraghi et al.
ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
Journal of University Medical & Dental College
Escherichia coli- Antimicrobial agents- Resistance
title ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
title_full ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
title_fullStr ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
title_full_unstemmed ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
title_short ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI ISOLATED FROM PATIENTS IN SHAHID SADOUGHI HOSPITAL, YAZD, IRAN
title_sort antibiotic resistance of escherichia coli isolated from patients in shahid sadoughi hospital yazd iran
topic Escherichia coli- Antimicrobial agents- Resistance
url http://jumdc.com/index.php/jumdc/article/view/239
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