Hypoxia Increases the Tempo of Phage Resistance and Mutational Bottlenecking of Pseudomonas aeruginosa

Hypoxia Increases the Tempo of Phage Resistance and Mutational Bottlenecking of Pseudomonas aeruginosa

Viruses that infect bacteria (i.e., phages) are abundant and widespread in the human body, and new anti-infective approaches such as phage therapy are essential for the future of effective medicine. Our understanding of microenvironmental factors such as tissue oxygen availability at the site of pha...

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Bibliographic Details
Main Authors: Ashley R. Schumann, Andrew D. Sue, Dwayne R. Roach
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
bacteriophages
hypoxia
oxygen
phage resistance
pyomelanin
phage therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.905343/full

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