Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228

Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228

FK228 is an FDA-approved anticancer drug naturally produced by Chromobacterium violaceum No. 968 up to 19 mg/L in a pilot industry-scale batch fermentation. Here we report a genomics-guided discovery of Burkholderia thailandensis MSMB43 as a new and significantly better source of FK228. The genome o...

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Bibliographic Details
Main Authors: Xiangyang Liu, Feng Xie, Leah B. Doughty, Qi Wang, Lixin Zhang, Xueting Liu, Yi-Qiang Cheng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-12-01
Series:Synthetic and Systems Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X18300619

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http://www.sciencedirect.com/science/article/pii/S2405805X18300619

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