Mitochondria and Inflammation: Cell Death Heats Up

Mitochondria and Inflammation: Cell Death Heats Up

Mitochondrial outer membrane permeabilization (MOMP) is essential to initiate mitochondrial apoptosis. Due to the disruption of mitochondrial outer membrane integrity, intermembrane space proteins, notably cytochrome c, are released into the cytosol whereupon they activate caspase proteases and apop...

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Bibliographic Details
Main Authors: Esmee Vringer, Stephen W. G. Tait
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mitochondria
cell death
inflammation
interferon
NF-κB
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00100/full

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