MR imaging of hypothalamic hamartoma in a patient with gelastic seizures
Hypothalamic hamartomas (HHs) are non-neoplastic malformations that occur in the region of the hypothalamus. HH is the leading cause of gelastic seizures in children and adolescents, where laughing is characteristically manifested. However, these patients can also experience different forms of compl...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-09-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043321004386 |
| _version_ | 1818354492495626240 |
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| author | Wan Ahmad Firdaus Wan Chek, MD Yong Guang Teh, MD, DrRad Dian Noriza Eddy Suryono, MB BCh BAO, MMed(Rad) Chiak Yot Ng, MBBS, MMed(Rad) Selim Ahmed, MBBS, FCPS, MPH |
| author_facet | Wan Ahmad Firdaus Wan Chek, MD Yong Guang Teh, MD, DrRad Dian Noriza Eddy Suryono, MB BCh BAO, MMed(Rad) Chiak Yot Ng, MBBS, MMed(Rad) Selim Ahmed, MBBS, FCPS, MPH |
| author_sort | Wan Ahmad Firdaus Wan Chek, MD |
| collection | DOAJ |
| description | Hypothalamic hamartomas (HHs) are non-neoplastic malformations that occur in the region of the hypothalamus. HH is the leading cause of gelastic seizures in children and adolescents, where laughing is characteristically manifested. However, these patients can also experience different forms of complex or generalized tonic-clonic seizures that can obscure the diagnosis of HHs. We present a case of a 10 year-old boy that experienced several seizure types, but was subsequently diagnosed with HH after MR imaging was performed. This case highlights the complementary role of MR imaging in ascertaining seizure etiololgy when the clinical history and EEG findings are non-specific. The importance of early diagnosis with MR imaging is further underscored by the fact that patients diagnosed with HH usually develop drug resistance towards antiepileptic drugs, mandating neurosurgical assessment and intervention. |
| first_indexed | 2024-12-13T19:26:17Z |
| format | Article |
| id | doaj.art-5670843ff2de4790af65c265a5e219bf |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-13T19:26:17Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-5670843ff2de4790af65c265a5e219bf2022-12-21T23:34:01ZengElsevierRadiology Case Reports1930-04332021-09-0116927062709MR imaging of hypothalamic hamartoma in a patient with gelastic seizuresWan Ahmad Firdaus Wan Chek, MD0Yong Guang Teh, MD, DrRad1Dian Noriza Eddy Suryono, MB BCh BAO, MMed(Rad)2Chiak Yot Ng, MBBS, MMed(Rad)3Selim Ahmed, MBBS, FCPS, MPH4Department of Radiology, Sabah Women & Childen's Hospital, Kota Kinabalu, Sabah, MalaysiaDepartment of Radiology, Sabah Women & Childen's Hospital, Kota Kinabalu, Sabah, Malaysia; Faculty of Medicine & Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia; Corresponding author.Department of Radiology, Sabah Women & Childen's Hospital, Kota Kinabalu, Sabah, MalaysiaFaculty of Medicine & Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, MalaysiaFaculty of Medicine & Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, MalaysiaHypothalamic hamartomas (HHs) are non-neoplastic malformations that occur in the region of the hypothalamus. HH is the leading cause of gelastic seizures in children and adolescents, where laughing is characteristically manifested. However, these patients can also experience different forms of complex or generalized tonic-clonic seizures that can obscure the diagnosis of HHs. We present a case of a 10 year-old boy that experienced several seizure types, but was subsequently diagnosed with HH after MR imaging was performed. This case highlights the complementary role of MR imaging in ascertaining seizure etiololgy when the clinical history and EEG findings are non-specific. The importance of early diagnosis with MR imaging is further underscored by the fact that patients diagnosed with HH usually develop drug resistance towards antiepileptic drugs, mandating neurosurgical assessment and intervention.http://www.sciencedirect.com/science/article/pii/S1930043321004386Hypothalamic hamartomasGelastic seizuresMR brainSeizure semiologyEEG |
| spellingShingle | Wan Ahmad Firdaus Wan Chek, MD Yong Guang Teh, MD, DrRad Dian Noriza Eddy Suryono, MB BCh BAO, MMed(Rad) Chiak Yot Ng, MBBS, MMed(Rad) Selim Ahmed, MBBS, FCPS, MPH MR imaging of hypothalamic hamartoma in a patient with gelastic seizures Radiology Case Reports Hypothalamic hamartomas Gelastic seizures MR brain Seizure semiology EEG |
| title | MR imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| title_full | MR imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| title_fullStr | MR imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| title_full_unstemmed | MR imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| title_short | MR imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| title_sort | mr imaging of hypothalamic hamartoma in a patient with gelastic seizures |
| topic | Hypothalamic hamartomas Gelastic seizures MR brain Seizure semiology EEG |
| url | http://www.sciencedirect.com/science/article/pii/S1930043321004386 |
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