THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES
Purpose: To study the dynamics of production and reception of angiogenic growth factors (epidermal growth factor (EGF), transforming growth factor-b (Smad-4)), to prove the role of a male factor in miscarriage.Materials and methods: 180 pregnant women (trimester I) divided into 3 clinical groups wer...
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| Format: | Article |
| Language: | English |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2013-12-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/160 |
| Summary: | Purpose: To study the dynamics of production and reception of angiogenic growth factors (epidermal growth factor (EGF), transforming growth factor-b (Smad-4)), to prove the role of a male factor in miscarriage.Materials and methods: 180 pregnant women (trimester I) divided into 3 clinical groups were included in the research. The material for the research was the blood serum taken in the gestation term of 8-10 weeks of pregnancy.Results: In case of miscarriage, the expression of the transforming growth factor-b (Smad-4) decreases. In 60% of cases the key role in miscarriages plays the male factor.Summary: In order to reduce the risk of reproductive losses, it is necessary to recommend couple examination to all patients with recurrent miscarriagefor pregravid preparation. |
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| ISSN: | 2219-8075 2618-7876 |