THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES
Purpose: To study the dynamics of production and reception of angiogenic growth factors (epidermal growth factor (EGF), transforming growth factor-b (Smad-4)), to prove the role of a male factor in miscarriage.Materials and methods: 180 pregnant women (trimester I) divided into 3 clinical groups wer...
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| Format: | Article |
| Language: | English |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2013-12-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/160 |
| _version_ | 1811189263366094848 |
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| author | Zh. A. Elzhorukaeva |
| author_facet | Zh. A. Elzhorukaeva |
| author_sort | Zh. A. Elzhorukaeva |
| collection | DOAJ |
| description | Purpose: To study the dynamics of production and reception of angiogenic growth factors (epidermal growth factor (EGF), transforming growth factor-b (Smad-4)), to prove the role of a male factor in miscarriage.Materials and methods: 180 pregnant women (trimester I) divided into 3 clinical groups were included in the research. The material for the research was the blood serum taken in the gestation term of 8-10 weeks of pregnancy.Results: In case of miscarriage, the expression of the transforming growth factor-b (Smad-4) decreases. In 60% of cases the key role in miscarriages plays the male factor.Summary: In order to reduce the risk of reproductive losses, it is necessary to recommend couple examination to all patients with recurrent miscarriagefor pregravid preparation. |
| first_indexed | 2024-04-11T14:31:53Z |
| format | Article |
| id | doaj.art-567587a1225d45ba9e9decafcba500cb |
| institution | Directory Open Access Journal |
| issn | 2219-8075 2618-7876 |
| language | English |
| last_indexed | 2024-04-11T14:31:53Z |
| publishDate | 2013-12-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj.art-567587a1225d45ba9e9decafcba500cb2022-12-22T04:18:30ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762013-12-010414514810.21886/2219-8075-2013-4-145-148159THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGESZh. A. Elzhorukaeva0Rostov Scientific and Research Institute of Obstetrics and PediatricsPurpose: To study the dynamics of production and reception of angiogenic growth factors (epidermal growth factor (EGF), transforming growth factor-b (Smad-4)), to prove the role of a male factor in miscarriage.Materials and methods: 180 pregnant women (trimester I) divided into 3 clinical groups were included in the research. The material for the research was the blood serum taken in the gestation term of 8-10 weeks of pregnancy.Results: In case of miscarriage, the expression of the transforming growth factor-b (Smad-4) decreases. In 60% of cases the key role in miscarriages plays the male factor.Summary: In order to reduce the risk of reproductive losses, it is necessary to recommend couple examination to all patients with recurrent miscarriagefor pregravid preparation.https://www.medicalherald.ru/jour/article/view/160miscarriageangiogenesisspermatogenesis |
| spellingShingle | Zh. A. Elzhorukaeva THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES Медицинский вестник Юга России miscarriage angiogenesis spermatogenesis |
| title | THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES |
| title_full | THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES |
| title_fullStr | THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES |
| title_full_unstemmed | THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES |
| title_short | THE ROLE OF ANGIOGENIC GROWTH FACTORS IN MISCARRIAGES |
| title_sort | role of angiogenic growth factors in miscarriages |
| topic | miscarriage angiogenesis spermatogenesis |
| url | https://www.medicalherald.ru/jour/article/view/160 |
| work_keys_str_mv | AT zhaelzhorukaeva theroleofangiogenicgrowthfactorsinmiscarriages AT zhaelzhorukaeva roleofangiogenicgrowthfactorsinmiscarriages |