Alternative splicing after gene duplication drives CEACAM1-paralog diversification in the horse

Alternative splicing after gene duplication drives CEACAM1-paralog diversification in the horse

Abstract Background The CEA gene family is one of the most rapidly evolving gene families in the human genome. The founder gene of the family is thought to be an ancestor of the inhibitory immune checkpoint molecule CEACAM1. Comprehensive analyses of mammalian genomes showed that the CEA gene family...

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Bibliographic Details
Main Authors: Sophie Mißbach, Denis Aleksic, Lisa Blaschke, Timm Hassemer, Kyung Jin Lee, Martin Mansfeld, Jana Hänske, Johannes Handler, Robert Kammerer
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Evolutionary Biology
Subjects:
Alternative splicing
Gene duplication
Horse
CEA gene family
CEACAM
Signaling motifs
Online Access:http://link.springer.com/article/10.1186/s12862-018-1145-x

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