Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela
Although cases of hyponatremia during pregnancy have been described, it has rarely been possible to show demyelination lesions in central pons, bulbus as well as thalamus, by imaging techniques. We report a case that developed extensive myelinolysis due to the “rapid” correction of hyponatremia as a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AVES
2012-12-01
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| Series: | Eurasian Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.eajm.org/summary_en.php3?id=461 |
| _version_ | 1797919231865520128 |
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| author | Mustafa Uzkeser Ayhan Akoz Gokhan Ozdemir Mucahit Emet Atif Bayramoglu |
| author_facet | Mustafa Uzkeser Ayhan Akoz Gokhan Ozdemir Mucahit Emet Atif Bayramoglu |
| author_sort | Mustafa Uzkeser |
| collection | DOAJ |
| description | Although cases of hyponatremia during pregnancy have been described, it has rarely been possible to show demyelination lesions in central pons, bulbus as well as thalamus, by imaging techniques. We report a case that developed extensive myelinolysis due to the “rapid” correction of hyponatremia as a result of hyperemesis gravidarum. Magnetic resonance imaging showed bilaterally symmetric hyperintense areas in the thalamus and cerebral crus and symmetric hyperintense area in the central pons, with sparing of the rim. In the second day of hospitalization, probably as a result of expansion of myelinolysis, she was intubated and received mechanical ventilator due to bradypnea and a GCS scale of E1M4V2. She was extubated in 11th day of hospitalization and physical therapy was started. She was discharged in 30th day of hospitalization with a GCS of 15. But she was tetraparetic (2/5). In the 3rd month of follow up, her quadriparesis improved to paraparesis in lower extremities (3/5). Her follow up examinations in the first year did not change although physical therapies go on. She delivered a normal child. |
| first_indexed | 2024-04-10T13:42:23Z |
| format | Article |
| id | doaj.art-5676051129d7473b9e8517df00b0b3ec |
| institution | Directory Open Access Journal |
| issn | 1308-8734 1308-8742 |
| language | English |
| last_indexed | 2024-04-10T13:42:23Z |
| publishDate | 2012-12-01 |
| publisher | AVES |
| record_format | Article |
| series | Eurasian Journal of Medicine |
| spelling | doaj.art-5676051129d7473b9e8517df00b0b3ec2023-02-15T16:11:07ZengAVESEurasian Journal of Medicine1308-87341308-87422012-12-01443179181Wide Central Pontine, Bulbar and Thalamic Myelinolysis with SequelaMustafa UzkeserAyhan AkozGokhan OzdemirMucahit EmetAtif BayramogluAlthough cases of hyponatremia during pregnancy have been described, it has rarely been possible to show demyelination lesions in central pons, bulbus as well as thalamus, by imaging techniques. We report a case that developed extensive myelinolysis due to the “rapid” correction of hyponatremia as a result of hyperemesis gravidarum. Magnetic resonance imaging showed bilaterally symmetric hyperintense areas in the thalamus and cerebral crus and symmetric hyperintense area in the central pons, with sparing of the rim. In the second day of hospitalization, probably as a result of expansion of myelinolysis, she was intubated and received mechanical ventilator due to bradypnea and a GCS scale of E1M4V2. She was extubated in 11th day of hospitalization and physical therapy was started. She was discharged in 30th day of hospitalization with a GCS of 15. But she was tetraparetic (2/5). In the 3rd month of follow up, her quadriparesis improved to paraparesis in lower extremities (3/5). Her follow up examinations in the first year did not change although physical therapies go on. She delivered a normal child.http://www.eajm.org/summary_en.php3?id=461Central ponsExtraponsHyperemesis gravidarumHyponatremiaMyelinolisis |
| spellingShingle | Mustafa Uzkeser Ayhan Akoz Gokhan Ozdemir Mucahit Emet Atif Bayramoglu Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela Eurasian Journal of Medicine Central pons Extrapons Hyperemesis gravidarum Hyponatremia Myelinolisis |
| title | Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela |
| title_full | Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela |
| title_fullStr | Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela |
| title_full_unstemmed | Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela |
| title_short | Wide Central Pontine, Bulbar and Thalamic Myelinolysis with Sequela |
| title_sort | wide central pontine bulbar and thalamic myelinolysis with sequela |
| topic | Central pons Extrapons Hyperemesis gravidarum Hyponatremia Myelinolisis |
| url | http://www.eajm.org/summary_en.php3?id=461 |
| work_keys_str_mv | AT mustafauzkeser widecentralpontinebulbarandthalamicmyelinolysiswithsequela AT ayhanakoz widecentralpontinebulbarandthalamicmyelinolysiswithsequela AT gokhanozdemir widecentralpontinebulbarandthalamicmyelinolysiswithsequela AT mucahitemet widecentralpontinebulbarandthalamicmyelinolysiswithsequela AT atifbayramoglu widecentralpontinebulbarandthalamicmyelinolysiswithsequela |