PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOS

PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOS

Abstract Background Gastric cancer (GC) is the fifth most common cancer and the third most common cause of cancer death worldwide. Plant homeodomain (PHD)-finger domain protein PHF5A has been demonstrated to play a promoting role in a variety of cancers. This study aimed to clarify the role of PHF5A...

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Bibliographic Details
Main Authors: Zhandong Zhang, Liangqun Peng, Wei Yang, Baodong Li, Yawei Hua, Suxia Luo
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
PHF5A
FOS
Phenotype
Ubiquitination
Online Access:https://doi.org/10.1186/s12967-022-03821-w

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