Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation

Nuclear Isoforms of Neurofibromin Are Required for Proper Spindle Organization and Chromosome Segregation

Mitotic spindles are highly organized, microtubule (MT)-based, transient structures that serve the fundamental function of unerring chromosome segregation during cell division and thus of genomic stability during tissue morphogenesis and homeostasis. Hence, a multitude of MT-associated proteins (MAP...

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Bibliographic Details
Main Authors:	Charoula Peta, Emmanouella Tsirimonaki, Dimitris Samouil, Kyriaki Georgiadou, Dimitra Mangoura
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Cells
Subjects:	neurofibromin neurofibromatosis astral microtubules astrocyte glioblastoma spindle assembly
Online Access:	https://www.mdpi.com/2073-4409/9/11/2348

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