A LINK BETWEEN AUTOPHAGY REGULATORY PROTEINS M-TOR AND BECLIN-1 AND PARAMETERS OF LYMPHOGENIC METASTASIS IN COLORECTAL CANCER

A LINK BETWEEN AUTOPHAGY REGULATORY PROTEINS M-TOR AND BECLIN-1 AND PARAMETERS OF LYMPHOGENIC METASTASIS IN COLORECTAL CANCER

Currently the impact of autophagy on carcinogenesis remains understudied. On the one hand, autophagy acts as a tumor suppressor, as it activates degradation of oncoproteins,  toxic proteins, and damaged cell organelles, that may be aggressive and lead to DNA  damage. On the other hand, autophagy may...

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Bibliographic Details
Main Authors: S. V. Vtorushin, K. V. Rachkovsky, N. V. Krakhmal, I. V. Stepanov, M. V. Zavyalova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2018-09-01
Series:Сибирский онкологический журнал
Subjects:
колоректальный рак
аутофагия
лимфогенное метастазирование
beclin-1
m-tor
прогноз
Online Access:https://www.siboncoj.ru/jour/article/view/814

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