Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries
Abstract Objective Green synthesized iron(III) oxide (Fe3O4) nanoparticles are gaining appeal in targeted drug delivery systems because of their low cost, fast processing and nontoxicity. However, there is no known research work undertaken in the production of green synthesized nano-particles from t...
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13104-022-06039-7 |
| _version_ | 1811289225054650368 |
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| author | Henry Fenekansi Kiwumulo Haruna Muwonge Charles Ibingira Michael Lubwama John Baptist Kirabira Robert Tamale Ssekitoleko |
| author_facet | Henry Fenekansi Kiwumulo Haruna Muwonge Charles Ibingira Michael Lubwama John Baptist Kirabira Robert Tamale Ssekitoleko |
| author_sort | Henry Fenekansi Kiwumulo |
| collection | DOAJ |
| description | Abstract Objective Green synthesized iron(III) oxide (Fe3O4) nanoparticles are gaining appeal in targeted drug delivery systems because of their low cost, fast processing and nontoxicity. However, there is no known research work undertaken in the production of green synthesized nano-particles from the Ugandan grown Moringa Oleifera (MO). This study aims at exploring and developing an optimized protocol aimed at producing such nanoparticles from the Ugandan grown Moringa. Results While reducing ferric chloride solution with Moringa oleifera leaves, Iron oxide nanoparticles (Fe3O4-NPs) were synthesized through an economical and completely green biosynthetic method. The structural properties of these Fe3O4-NPs were investigated by Ultra Violet–visible (UV–Vis) spectrophotometry, X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM). These nanoparticles exhibited UV–visible absorption peaks at 225 nm (nm) for the sixth dilution and 228 nm for the fifth dilution which indicated that the nanoparticles were photosensitive and the SEM study confirmed the spherical nature of these nanoparticles. The total synthesis time was approximately 5 h after drying the moringa leaves, and the average particle size was approximately 16 nm. Such synthesized nanoparticles can potentially be useful for drug delivery, especially in Low and Middle Income Countries (LMICs). |
| first_indexed | 2024-04-13T03:51:09Z |
| format | Article |
| id | doaj.art-56875d5446e04abcaff65d524ad3afad |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-13T03:51:09Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-56875d5446e04abcaff65d524ad3afad2022-12-22T03:03:48ZengBMCBMC Research Notes1756-05002022-04-011511810.1186/s13104-022-06039-7Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countriesHenry Fenekansi Kiwumulo0Haruna Muwonge1Charles Ibingira2Michael Lubwama3John Baptist Kirabira4Robert Tamale Ssekitoleko5Department of Medical Physiology, Makerere UniversityDepartment of Medical Physiology, Makerere UniversityDepartment of Human Anatomy, Makerere UniversityDepartment of Mechanical Engineering, Makerere UniversityDepartment of Mechanical Engineering, Makerere UniversityDepartment of Medical Physiology, Makerere UniversityAbstract Objective Green synthesized iron(III) oxide (Fe3O4) nanoparticles are gaining appeal in targeted drug delivery systems because of their low cost, fast processing and nontoxicity. However, there is no known research work undertaken in the production of green synthesized nano-particles from the Ugandan grown Moringa Oleifera (MO). This study aims at exploring and developing an optimized protocol aimed at producing such nanoparticles from the Ugandan grown Moringa. Results While reducing ferric chloride solution with Moringa oleifera leaves, Iron oxide nanoparticles (Fe3O4-NPs) were synthesized through an economical and completely green biosynthetic method. The structural properties of these Fe3O4-NPs were investigated by Ultra Violet–visible (UV–Vis) spectrophotometry, X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM). These nanoparticles exhibited UV–visible absorption peaks at 225 nm (nm) for the sixth dilution and 228 nm for the fifth dilution which indicated that the nanoparticles were photosensitive and the SEM study confirmed the spherical nature of these nanoparticles. The total synthesis time was approximately 5 h after drying the moringa leaves, and the average particle size was approximately 16 nm. Such synthesized nanoparticles can potentially be useful for drug delivery, especially in Low and Middle Income Countries (LMICs).https://doi.org/10.1186/s13104-022-06039-7Green synthesisBio-compatibleIron oxide nanoparticlesMoringa oleiferaLMICsUV–vis |
| spellingShingle | Henry Fenekansi Kiwumulo Haruna Muwonge Charles Ibingira Michael Lubwama John Baptist Kirabira Robert Tamale Ssekitoleko Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries BMC Research Notes Green synthesis Bio-compatible Iron oxide nanoparticles Moringa oleifera LMICs UV–vis |
| title | Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries |
| title_full | Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries |
| title_fullStr | Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries |
| title_full_unstemmed | Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries |
| title_short | Green synthesis and characterization of iron-oxide nanoparticles using Moringa oleifera: a potential protocol for use in low and middle income countries |
| title_sort | green synthesis and characterization of iron oxide nanoparticles using moringa oleifera a potential protocol for use in low and middle income countries |
| topic | Green synthesis Bio-compatible Iron oxide nanoparticles Moringa oleifera LMICs UV–vis |
| url | https://doi.org/10.1186/s13104-022-06039-7 |
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