Developmental defects of enamel in children born preterm
IntroductionTo investigate manifestations of developmental defects of enamel (DDE) in children born preterm (PT), and to explore possible neonatal morbidities related to DDE manifestation and severity.MethodsA cohort study of 52 children born before gestational week 32 and treated in the neonatal in...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.1019586/full |
| _version_ | 1797995585026916352 |
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| author | Elinor Halperson Salome Shafir Avia Fux-Noy Diana Ram Smadar Eventov-Friedman |
| author_facet | Elinor Halperson Salome Shafir Avia Fux-Noy Diana Ram Smadar Eventov-Friedman |
| author_sort | Elinor Halperson |
| collection | DOAJ |
| description | IntroductionTo investigate manifestations of developmental defects of enamel (DDE) in children born preterm (PT), and to explore possible neonatal morbidities related to DDE manifestation and severity.MethodsA cohort study of 52 children born before gestational week 32 and treated in the neonatal intensive care unit; and 55 children born at full term (FT) as a control group. All the children had a dental examination at age 1–4 years by a professional pediatric dentist. DDE was defined as an alteration in the enamel surface.ResultsDDE were observed in 23 (44%) and 6 (11%) children, in the PT and FT groups, respectively, odds ratio (OR) = 6.47. The OR for damaged anterior teeth was 12.87 times higher in the PT group. DDE of molars was diagnosed in 19% and 11% of the respective groups. In the PT group, the OR of DDE was 4.1 higher among those with than without respiratory distress. The risk for DDE was 5.7 higher in those who received surfactant than in those who did not. Ventilation length, both invasive and non-invasive, was significantly related to DEE.ConclusionsDDE was higher in children born PT than FT. The DDE rate was lower than expected based on current literature, and considering the overall increase in survival; this suggests improvement in treatments affecting DEE. Respiratory distress syndrome, surfactant administration reflecting the need for intubation, longer ventilation and local oral trauma were risk factors for DDE. We recommend routine dental examinations in follow up of children born PT, particularly those exposed to assisted ventilation. |
| first_indexed | 2024-04-11T10:03:55Z |
| format | Article |
| id | doaj.art-5687dd5fd5bb4cb79f0eb40876396c2d |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T10:03:55Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-5687dd5fd5bb4cb79f0eb40876396c2d2022-12-22T04:30:17ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-10-011010.3389/fped.2022.10195861019586Developmental defects of enamel in children born pretermElinor Halperson0Salome Shafir1Avia Fux-Noy2Diana Ram3Smadar Eventov-Friedman4Department of Pediatric Dentistry, Hadassah Medical Center and Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Pediatric Dentistry, Hadassah Medical Center and Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Pediatric Dentistry, Hadassah Medical Center and Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Pediatric Dentistry, Hadassah Medical Center and Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelDepartment of Neonatology, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, IsraelIntroductionTo investigate manifestations of developmental defects of enamel (DDE) in children born preterm (PT), and to explore possible neonatal morbidities related to DDE manifestation and severity.MethodsA cohort study of 52 children born before gestational week 32 and treated in the neonatal intensive care unit; and 55 children born at full term (FT) as a control group. All the children had a dental examination at age 1–4 years by a professional pediatric dentist. DDE was defined as an alteration in the enamel surface.ResultsDDE were observed in 23 (44%) and 6 (11%) children, in the PT and FT groups, respectively, odds ratio (OR) = 6.47. The OR for damaged anterior teeth was 12.87 times higher in the PT group. DDE of molars was diagnosed in 19% and 11% of the respective groups. In the PT group, the OR of DDE was 4.1 higher among those with than without respiratory distress. The risk for DDE was 5.7 higher in those who received surfactant than in those who did not. Ventilation length, both invasive and non-invasive, was significantly related to DEE.ConclusionsDDE was higher in children born PT than FT. The DDE rate was lower than expected based on current literature, and considering the overall increase in survival; this suggests improvement in treatments affecting DEE. Respiratory distress syndrome, surfactant administration reflecting the need for intubation, longer ventilation and local oral trauma were risk factors for DDE. We recommend routine dental examinations in follow up of children born PT, particularly those exposed to assisted ventilation.https://www.frontiersin.org/articles/10.3389/fped.2022.1019586/fullenamelpretermteethsurfactantventilation |
| spellingShingle | Elinor Halperson Salome Shafir Avia Fux-Noy Diana Ram Smadar Eventov-Friedman Developmental defects of enamel in children born preterm Frontiers in Pediatrics enamel preterm teeth surfactant ventilation |
| title | Developmental defects of enamel in children born preterm |
| title_full | Developmental defects of enamel in children born preterm |
| title_fullStr | Developmental defects of enamel in children born preterm |
| title_full_unstemmed | Developmental defects of enamel in children born preterm |
| title_short | Developmental defects of enamel in children born preterm |
| title_sort | developmental defects of enamel in children born preterm |
| topic | enamel preterm teeth surfactant ventilation |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.1019586/full |
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