Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions

Introduction: The febrile convulsion (FC) occurs in neurologically normal children aged between six months and five years and it is defined as convulsions occurred during fever and in the absence of central nervous system (CNS) infection, electrolyte imbalance, diseases affecting directly CNS, and h...

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Main Authors: Erhan Berk, Ali Kaya, Köksal Deveci, Ahmet Sami Güven, Mevlüt Demir, Hatice Güneş, Asım Gültekin, Füsun Dilara İçağasıoğlu
Format: Article
Language:English
Published: Galenos Publishing House 2011-12-01
Series:Güncel Pediatri
Subjects:
Online Access:http://www.guncelpediatri.com/eng/makale/3181/100/Full-Text
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author Erhan Berk
Ali Kaya
Köksal Deveci
Ahmet Sami Güven
Mevlüt Demir
Hatice Güneş
Asım Gültekin
Füsun Dilara İçağasıoğlu
author_facet Erhan Berk
Ali Kaya
Köksal Deveci
Ahmet Sami Güven
Mevlüt Demir
Hatice Güneş
Asım Gültekin
Füsun Dilara İçağasıoğlu
author_sort Erhan Berk
collection DOAJ
description Introduction: The febrile convulsion (FC) occurs in neurologically normal children aged between six months and five years and it is defined as convulsions occurred during fever and in the absence of central nervous system (CNS) infection, electrolyte imbalance, diseases affecting directly CNS, and history of afebrile convulsion. The aims of this study were to determine the serum levels of selenium in patients with recurrent FC and to compare them with those of healthy children. Materials and Methods: The study included 61 pediatric patients diagnosed with recurrent FC. At the same session, 54 healthy children who admitted to our pediatric clinic for routine controls without history of fever and convulsion, are assigned as control group. The serum level of selenium was measured by atomic absorption spectrometric method (hydride technique).Results: Mean level of selenium was determined as 67.10±8.87 µg/L in patients and 81.99±13.13 µg/L in control group; the difference was statistically significant (p<0.05). Discussion: The lower serum levels of selenium in patients with recurrent FC may be the cause of triggering of convulsion or may contribute to its recurrence. Further studies are necessary to clarify this relationship. (Jo­ur­nal of Cur­rent Pe­di­at­rics 2011; 9: 110-5)
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spelling doaj.art-568cde4bec13410fbce9fb42ffd749882025-01-02T17:10:38ZengGalenos Publishing HouseGüncel Pediatri1304-90542011-12-0193110115Evaluation of Serum Selenium Levels in Children with Recurrent Febril ConvulsionsErhan BerkAli KayaKöksal DeveciAhmet Sami GüvenMevlüt DemirHatice GüneşAsım GültekinFüsun Dilara İçağasıoğluIntroduction: The febrile convulsion (FC) occurs in neurologically normal children aged between six months and five years and it is defined as convulsions occurred during fever and in the absence of central nervous system (CNS) infection, electrolyte imbalance, diseases affecting directly CNS, and history of afebrile convulsion. The aims of this study were to determine the serum levels of selenium in patients with recurrent FC and to compare them with those of healthy children. Materials and Methods: The study included 61 pediatric patients diagnosed with recurrent FC. At the same session, 54 healthy children who admitted to our pediatric clinic for routine controls without history of fever and convulsion, are assigned as control group. The serum level of selenium was measured by atomic absorption spectrometric method (hydride technique).Results: Mean level of selenium was determined as 67.10±8.87 µg/L in patients and 81.99±13.13 µg/L in control group; the difference was statistically significant (p<0.05). Discussion: The lower serum levels of selenium in patients with recurrent FC may be the cause of triggering of convulsion or may contribute to its recurrence. Further studies are necessary to clarify this relationship. (Jo­ur­nal of Cur­rent Pe­di­at­rics 2011; 9: 110-5)http://www.guncelpediatri.com/eng/makale/3181/100/Full-TextFebrile seizuresseleniumantioxidant system
spellingShingle Erhan Berk
Ali Kaya
Köksal Deveci
Ahmet Sami Güven
Mevlüt Demir
Hatice Güneş
Asım Gültekin
Füsun Dilara İçağasıoğlu
Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
Güncel Pediatri
Febrile seizures
selenium
antioxidant system
title Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
title_full Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
title_fullStr Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
title_full_unstemmed Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
title_short Evaluation of Serum Selenium Levels in Children with Recurrent Febril Convulsions
title_sort evaluation of serum selenium levels in children with recurrent febril convulsions
topic Febrile seizures
selenium
antioxidant system
url http://www.guncelpediatri.com/eng/makale/3181/100/Full-Text
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